Results 101 to 110 of about 296,712 (303)

Full‐Field Damage Monitoring in Architected Lattices Using In situ Electrical Impedance Tomography

Advanced Functional Materials, EarlyView.
In situ electrical impedance tomography (EIT) turns 3D‐printed, CNT‐infused architected lattices into full‐field damage‐imaging systems. Tunable Voronoi‐based geometries act as active sensing architectures, enabling conductivity maps to detect early‐stage damage and localise sequential ligament fracture before catastrophic failure.
Akash Deep, Andrea Samore, Alistair McEwan, Andrew McBride, Shanmugam Kumar   +4 more
wiley   +1 more source

Inhibition of Gamma-Secretase Promotes Axon Regeneration After a Complete Spinal Cord Injury

Frontiers in Cell and Developmental Biology, 2020
In a recent study, we showed that GABA and baclofen (a GABAB receptor agonist) inhibit caspase activation and promote axon regeneration in descending neurons of the sea lamprey brainstem after a complete spinal cord injury (Romaus-Sanjurjo et al., 2018a).
Daniel Sobrido-Cameán, Diego Robledo, Daniel Romaus-Sanjurjo, Vanessa Pérez-Cedrón, Laura Sánchez, María Celina Rodicio, Antón Barreiro-Iglesias   +6 more
doaj   +1 more source

"Notch-Off": a perspective on the termination of Notch signalling

The International Journal of Developmental Biology, 2009
During Notch mediated lateral inhibition, interacting cells establish or amplify differences in Notch signalling, which are then translated into distinct cell fate decisions according to the developmental context. In recent years, several mechanisms that increase the signalling capacity of interacting cells have been uncovered (reviewed in Bray, 2006 ...
Rita, Fior, Domingos, Henrique
openaire   +3 more sources

Probing the druggability of the Notch1 ankyrin domain using a fragment-based approach [PDF]

, 2011
Notch signalling is a highly conserved pathway that is important in the developmental processes that control cell differentiation and cell fates. This canonical pathway involves binding of a transmembrane ligand in one cell to the extraceullular domain ...

core   +2 more sources

Intracrystalline Void‐Mediated Toughening of Brittle Crystals in Quail Eggshells

Advanced Functional Materials, EarlyView.
In quail eggshells, the high density and disordered arrangement of intracrystalline voids inhibit lattice cleavage, suppress long‐range crack propagation, and promote deformation twinning and quasi‐plasticity, serving as an essential toughening motif. We show that these voids remain within a narrow subcritical size range and therefore predominantly do ...
Jingxiao Zhong, Qihang Wang, Andre E. Vellwock, Sinuhe Perea Puente, Tingting Zhu, Jia Hui Lim, Kadda Medjoubi, Sebastian Hoerl, Erika Griesshaber, Wolfgang W. Schmahl, Yannicke Dauphin, Emeline Raguin, Peter Werner, Francesco Stellacci, Michael V. Swain, Peter Fratzl, Shahrouz Amini   +16 more
wiley   +1 more source

Designing a Compact Microstrip Antenna Using the Machine Learning Approach

Journal of Telecommunications and Information Technology, 2020
This paper presents how machine learning techniques may be applied in the process of designing a compact dual-band H-shaped rectangular microstrip antenna (RMSA) operating in 0.75–2.20 GHz and 3.0–3.44 GHz frequency ranges.
Kanhaiya Sharma, Ganga Prasad Pandey
doaj   +1 more source

Ultra‐Thin Tow‐Based Discontinuous Composites—Material Overview and Aspirations

Advanced Functional Materials, EarlyView.
Tow‐based discontinuous composites made from ultra‐thin tapes offer outstanding in‐plane mechanical properties. This material, inspired by Nacre, has high volume fraction of tapes exceeding 90 % and allows for quasi‐isotropic material plates less than 100 micrometer in thickness.
Ioannis Katsivalis, Vasiliki Safranoglou, Luis Gulfo, Michael R. Wisnom, Martin Fagerström, Malin Åkermo, Soraia Pimenta, Dan Zenkert, Leif E. Asp   +8 more
wiley   +1 more source

Glenoid Paralabral Cysts Causing Shoulder Pain and Isolated Infraspinatus Weakness: Early Arthroscopic Decompression and Labral Repair Leads to Complete Recovery: A Case Series

Journal of Orthopaedic Case Reports
Introduction: Shoulder pain in young patients can be caused by various conditions such as tendinitis, bursitis, capsulitis, and labral tears. Superior labrum anterior to posterior (SLAP) tears can sometimes be associated with a paralabral cyst, which can
Nandu M S Nair, B H Banarji, Kamal Jain, Aditya Reddy   +3 more
doaj   +1 more source

KSHV and the Role of Notch Receptor Dysregulation in Disease Progression

Pathogens, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of two human cancers, Kaposi’s Sarcoma (KS) and primary effusion lymphoma (PEL), and a lymphoproliferation, Multicentric Castleman’s Disease (MCD).
Jennifer L. DeCotiis, David M. Lukac
doaj   +1 more source

Epithelial Notch signaling regulates lung alveolar morphogenesis and airway epithelial integrity

, 2017
Abnormal enlargement of the alveolar spaces is a hallmark of conditions such as chronic obstructive pulmonary disease and bronchopulmonary dysplasia.
林泰元;曹伯年;魏淑?, Tsao, Po-Nien;Matsuoka, Chisa;Wei, Shu-Chen;Sato, Atsuyasu;Sato, Susumu;Hasegawa, Koichi;Chen, Hung-kuan;Ling, Thai-Yen;Mori, Munemasa;Cardoso, Wellington V.;Morimoto, Mitsuru   +1 more
core   +1 more source