Results 211 to 220 of about 566,967 (348)

Loss of the distal-proximal GLP-1/Notch activation gradient in the aging <i>C. elegans</i> germline. [PDF]

MicroPubl Biol
Janse van Vuuren R, Martel PO, Narbonne P.   +2 more
europepmc   +1 more source

On the feasibility of the Chevron Notch Beam method to measure fracture toughness of fine-grained zirconia ceramics

, 2016
Andreas Kailer, Marc Stephan
openalex   +2 more sources

A Critical Role for Notch Signaling in the Formation of Cholangiocellular Carcinomas [PDF]

, 2013
Steffen Zender, Irina Nickeleit, Torsten Wüestefeld, Inga Sörensen, Daniel Dauch, Przemyslaw Bozko, M. El-Khatib, Robert Geffers, Hueseyin Bektas, Michael P. Manns, Achim Gossler, Ludwig Wilkens, Ruben R. Plentz, Lars Zender, Nisar P. Malek   +14 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Design of a UWB Interference-Rejection LNA Based on a Q-Enhanced Notch Filter. [PDF]

Micromachines (Basel)
Li J, Fan Y, Meng F.
europepmc   +1 more source

Notch [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Notch 1 Impairs Osteoblastic Cell Differentiation [PDF]

, 2003
Maria P. Sciaudone, Elisabetta Gazzerro, Leah Priest, Anne M. Delany, Ernesto Canalis   +4 more
openalex   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Cldn11 deficiency aggravates osteoarthritis by inhibiting Notch signalling in a Tspan5-dependent manner. [PDF]

J Orthop Surg Res
Yu X, Li Y, Chen X, Cheng J, Yu X, Xu X, Xiao Q, Zhu X, Ke C.   +8 more
europepmc   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source