Results 261 to 270 of about 566,967 (348)

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Differential <i>Hes1</i> activation defines neural stem cell lineage commitment and niche maintenance in embryonic and adult mouse cortex. [PDF]

Proc Natl Acad Sci U S A
Riya PA, Jose R, Meera V, Basu B, Surya S, Aryasree R, Jyothi NP, Parvathy S, Dhanesh SB, Sanalkumar R, Praz V, Riggi N, James J.   +12 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Correlated Expression of Notch2 and ADAM17 in Primary Sjögren's Syndrome Salivary Glands. [PDF]

J Clin Med
Sisto M, Lisi S, Tamma R, De Giorgis M, Ingravallo G, Della Mura M, Sorino J, Cascardi E, Ribatti D.   +8 more
europepmc   +1 more source

Human placenta mesenchymal stem cells suppress airway inflammation in asthmatic rats by modulating Notch signaling

, 2018
Yuanyuan Li, Tiantian Qu, Lijun Tian, Tingting Han, Yongjun Jin, Yuesi Wang   +5 more
openalex   +2 more sources

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Single-cell transcriptomics reveals notch regulation in quiescent LEPR⁺ endometrial mesenchymal stem cells. [PDF]

Stem Cell Res Ther
Fang Y, Cao D, Lee CL, Chiu PCN, Ng EHY, Yeung WSB, Chan RWS.   +6 more
europepmc   +1 more source

Experimental and Numerical Study on Flexural Behavior of Concrete Beam With Notch and Repairing Materials

Waseem S. Khan, Saleem Akhtar, Aruna Rawat, A. Basu   +3 more
openalex   +2 more sources

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

<i>Drosophila</i> and mouse intestinal stem cells are spatiotemporally specified by Notch suppression and Wnt activation. [PDF]

Sci Adv
Wu Y, Yu L, Yu Y, Wu S, Yuan Q, Duan W, Cai S, Xiong B, Lin R, Guo Z.   +9 more
europepmc   +1 more source