Results 171 to 180 of about 16,426 (214)
Genetic depletion or pharmacological degradation of EZH2 attenuates renal fibrosis via suppressing Notch signaling. [PDF]
Clin EpigeneticsYu C +8 more
europepmc +1 more source
NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
, 2022 Abstract Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease and no preventive or curative therapy is available.
Daniel V. Oliveira +11 more
openaire +2 more sources
Pathological Notch3 aggregation [PDF]
, 2016 Zerebrale Mikroangiopathien sind die häufigste Ursache für Langzeitbehinderung und vaskuläre Demenz. Sie sind durch pathologische Prozesse charakterisiert, die die Struktur und Funktion der Mikrovaskulatur im Gehirn beeinträchtigen und dadurch zu Schädigungen der weißen und tiefen grauen Substanz führen.
Fresser, Patrizia
openaire +2 more sources
Notch3 orchestrates epithelial and inflammatory responses to promote acute kidney injury
Kidney International, 2018 International audienceAcute kidney injury is a major risk factor for subsequent chronic renal and/or cardiovascular complications. Previous studies have shown that Notch3 was de novo expressed in the injured renal epithelium in the early phases of ...
Panagiotis Kavvadas +2 more
exaly +2 more sources