Results 181 to 190 of about 15,431 (206)

Association between ischemic stroke, hemorrhagic stroke, dementia, and rs201118034 among general Taiwanese population. [PDF]

Alzheimers Dement
Liaw YC, Chen CH, Hsu SY, Liaw YC, Liaw YP.   +4 more
europepmc   +1 more source

Molecular impact of NOTCH signaling dysregulation on ovarian cancer progression, chemoresistance, and taxane response. [PDF]

Biomed Pharmacother
Koucka K, Spalenkova A, Seborova K, Tesarova T, Ehrlichova M, Krus I, Holy P, Rob L, Hruda M, Bouda J, Bartakova A, Smoligova V, Ojima I, Chen L, Bendale H, Mrhalova M, Kopeckova K, Soucek P, Vaclavikova R.   +18 more
europepmc   +1 more source

Notch Signaling Pathway Regulates Ozone-Induced Lung Circadian Rhythm Disruption. [PDF]

Toxics
Zhang X, Jian X, Miao X, Jia Y.
europepmc   +1 more source

Multiomic profiling reveals pericyte and smooth muscle cell contributions to CADASIL pathology in cell-specific Notch3 mutant mice

Huang Y, Clementel V, Zhang M, Martinez K, Martinez K, Spillard G, Torres-Sepulveda C, Kisler K, Coba MP, Rust R.   +9 more
europepmc   +1 more source

Vascular NOTCH3 Deposition Load

Cheng, Yu-Wen, Chen, Chih-Hao, Chao, Chi-Chao, Chen, Ya-Fang, Jeng, Jiann-Shing, Tang, Sung-Chun, Hsieh, Sung-Tsang   +6 more
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Pathological Notch3 aggregation

2016
Zerebrale Mikroangiopathien sind die häufigste Ursache für Langzeitbehinderung und vaskuläre Demenz. Sie sind durch pathologische Prozesse charakterisiert, die die Struktur und Funktion der Mikrovaskulatur im Gehirn beeinträchtigen und dadurch zu Schädigungen der weißen und tiefen grauen Substanz führen.
openaire   +1 more source

NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model

2022
AbstractCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic form of familial small vessel disease and no preventive or curative therapy is available. CADASIL is caused by mutations in the NOTCH3 gene, resulting in a mutated NOTCH3 receptor, with aggregation of the NOTCH3 ...
Daniel V. Oliveira, Kirsten G. Coupland, Shaobo Jin, Francesca Del Gaudio, Sailan Wang, Rhys Fox, Julie W. Rutten, Johan Sandin, Johan Lundkvist, Saskia A. J. Lesnik Oberstein, Urban Lendahl, Helena Karlström   +11 more
openaire   +1 more source

Transendocytosis is impaired in CADASIL-mutant NOTCH3

Experimental Neurology, 2012
Mutations in the human NOTCH3 gene cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), but the pathogenesis of CADASIL has remained unclear. Recently, endocytosis of the Notch ectodermal domain into ligand-expressing cells, called transendocytosis, has come to be considered critical for Notch ...
Akiko, Watanabe-Hosomi, Yoshihisa, Watanabe, Masaki, Tanaka, Masanori, Nakagawa, Toshiki, Mizuno   +4 more
openaire   +2 more sources