Results 181 to 190 of about 136,068 (264)

Unlocking Strength‐Toughness Dilemma in High‐Entropy Borides by Intragranular Microstructural Reconstruction

Advanced Science, EarlyView.
An extreme non‐equilibrium process combining heavy direct current sintering and TiSi2 addition is used to construct intragranular energy dissipation units within high‐entropy boride ceramics to overcome the strength‐toughness trade‐off. The resulting ceramic demonstrates attractive mechanical properties with a flexural strength of 887 MPa and a ...
Yingjun Liu, Yuhan Yao, Yufei Zu, Zhaofu Zhang, Yang Zhang, Hongfeng Dong, Nan Zhang, Wuhao Cao, Lehao Liu, Yuan Hu, Ruiheng An, Wenhu Li, Luyi Zhu, Taotao Ai   +13 more
wiley   +1 more source

Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development. [PDF]

Arterioscler Thromb Vasc Biol
Van Wauwe J, Janarthanan P, Craps S, Kc A, Asuncion L, Vrancaert P, Kemps H, Daems M, Finck C, Wright S, Müller C, Leigh ND, Renné T, Ola R, Panáková D, Frye M, MacRae CA, Luttun A, Beerens M.   +18 more
europepmc   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Computational Vascular Development Model Explaining Incidence of Notch in Retinopathy of Prematurity With Ultra-Widefield Optical Coherence Tomography. [PDF]

Invest Ophthalmol Vis Sci
Sutter DA, Igelman A, Coyner AS, Stratis G, Real K, Woodward MK, Jackson J, Bayhaqi Y, Ni S, Ostmo S, Jian Y, Chiang MF, Campbell JP, Guidoboni G, Young BK.   +14 more
europepmc   +1 more source

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

Advanced Science, EarlyView.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie, Mengyan Zhu, Zhongxian Zhu, Jiaqi Tang, Ruyi Zhang, Zequan Ding, Junzhi Li, Zhongluan Wu, Paul Kwong Hang Tam, Qianghu Wang, Vincent Chi Hang Lui, Yankai Xia, Weibing Tang   +12 more
wiley   +1 more source

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review). [PDF]

Oncol Lett
Guo X, Zhou X, Ran W, Zhu Q, Chen W, Ma C.   +5 more
europepmc   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Effect of Supplementary Notch on the U Notch in a Plate under Pure Bending

Journal of the Society of Materials Science, Japan, 1964
MURAKAMI, Yasunori, KAWABE, Toshio
openaire   +2 more sources

One‐Step Preparation of Lanthanide‐Doped Polyurea Multicolor Microspheres for Versatile Fluorescent Applications

Advanced Science, EarlyView.
Lanthanide‐doped polyurea microspheres are prepared via a facile one‐step precipitation polymerization. They exhibit strong hydrogen‐bonding and coordination interactions with excellent properties, including multicolor emission, high quantum yield (75.3%), remarkable stability, redispersibility, and biocompatibility.
Guiyu Zhang, Xiaoxia Yu, Xinhui Wang, Xiang Zheng Kong, Xiangling Gu, Jitao Liu, Shusheng Li, Xiaoli Zhu, Lianbao Cao, Xubao Jiang   +9 more
wiley   +1 more source

Researches on the Notch Effect of Materials : The 5th Report, on the Notch Effect at the Reentrant Corner of a Crank Shaft

Transactions of the Japan Society of Mechanical Engineers, 1952
KAWAMOTO, Minoru, NISHIOKA, Kunio
openaire   +2 more sources