Results 171 to 180 of about 136,068 (264)

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

open access: yesAdvanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai   +16 more
wiley   +1 more source

Fracture and Fatigue Assessment of Bonded Composite Patch Repairs in Notched and Cracked Plates. [PDF]

open access: yesPolymers (Basel)
Beylergil B   +6 more
europepmc   +1 more source

Hierarchical Twin Networks Enable Exceptional Strength and Fracture Toughness in Titanium

open access: yesAdvanced Science, EarlyView.
A commercial‐purity titanium with hierarchical ultrafine twin structures delivers an exceptional combination of fracture toughness (KJIc) of 187 MPa·m1/2 and specific yield strength of 140 MPa·cm3·g−1, in which pre‐engineered high‐density twin boundaries stimulate massive and dislocations to blunt crack tip.
Xiao‐Wei Zou  
+3 more
wiley   +1 more source

Scale Effects in Notch Brittleness

open access: yesJournal of the Japan Welding Society, 1953
openaire   +2 more sources

Local-nonlocal assisted multifunctional photonic crystals. [PDF]

open access: yesLight Sci Appl
Lv W   +9 more
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao   +8 more
wiley   +1 more source

Exclusion of Notch from the contact site during efferocytosis restricts anticancer immunity. [PDF]

open access: yesNat Immunol
Li Z   +10 more
europepmc   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

open access: yesAdvanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu   +10 more
wiley   +1 more source

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