Results 91 to 100 of about 156,496 (347)

Promotion of proliferation and metastasis of hepatocellular carcinoma by LncRNA00673 based on the targeted-regulation of notch signaling pathway [PDF]

, 2017
we read with great interest the paper by Dr. Chen et al1, recently published in European Review for Medical and Pharmacological Sciences and titled ‘‘Promotion of proliferation and metastasis of hepatocellular carcinoma by LncRNA00673 based on the ...
Assirati G, Ballarin R, Battistelli C, Di Benedetto F, Guerrini GP, Magistri P, Mereu F, Tarantino G   +7 more
core  

Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep [PDF]

, 2018
Additional file 6: Decreased lag-2 function does not slow vulval development. The progeny of wild type and lag-2(q420) animals raised at 25.5 °C were selected at the L4 stage, prior to lethargus entry. Vulval eversion was scored after 3 h; the percentage
Bennett, Heather L, Biron, David, Hart, Anne C, Hayden, Dustin, Huang, Huiyan, Khoruzhik, Yulia, Sanders, Jarred, Walsh, Melissa B   +7 more
core   +4 more sources

Meningioma Transcript Profiles Reveal Deregulated Notch Signaling Pathway [PDF]

Cancer Research, 2005
Abstract Meningiomas constitute the second most common central nervous system tumor, and yet relatively little is known about the molecular events that are important for the pathogenesis and malignant progression of these tumors. We have used serial analysis of gene expression to compare the transcriptomes of nonneoplastic meninges and ...
Ileana C, Cuevas, Alison L, Slocum, Peter, Jun, Joseph F, Costello, Andrew W, Bollen, Gregory J, Riggins, Michael W, McDermott, Anita, Lal   +7 more
openaire   +2 more sources

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. [PDF]

, 2017
Glioblastoma (GBM) stem cells (GSCs) reside in both hypoxic and vascular microenvironments within tumors. The molecular mechanisms that allow GSCs to occupy such contrasting niches are not understood.
Barcellos-Hoff, Mary Helen, Bayin, N Sumru, Chesler, Mitch, Chiriboga, Luis, Dolgalev, Igor, Doyle, Werner, Frenster, Joshua D, Galifianakis, Nataliya, Golfinos, John G, Heguy, Adriana, Illa-Bochaca, Irineu, Khahera, Anadjeet, Modrek, Aram S, Ortenzi, Valerio, Placantonakis, Dimitris G, Sen, Rajeev, Serrano, Jonathan, Si, Sheng, Snuderl, Matija, Tsirigos, Aristotelis, Zagzag, David   +20 more
core   +1 more source

The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]

, 2016
Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M., Fan, Wenhong, Liu, Shuang, Mitra, Ramkrishna, Yin, Feng, Zhao, Ming-Ming, Zhao, Zhongming   +6 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

TLR3 Gene Regulates Cataract-Related Mechanisms Through The Jagged-1/Notch Signaling Pathway [PDF]

, 2022
Yu Chen, Rui Yang
openalex   +1 more source

Thermal Phase‐Modulation of Thickness‐Dependent CVD‐Grown 2D In2Se3

Advanced Functional Materials, EarlyView.
A comprehensive study of CVD‐grown 2D In2Se3 reveals a distinct thickness‐dependent phase landscape and a reversible, thermally driven transformation between β″ and β* variants. In situ TEM electron diffraction and Raman spectroscopy reveal structural dynamics, while the structural invariance of the α‐phase in ultrathin regimes highlights its stability—
Dasun P. W. Guruge, Zhenhuan Chen, Joseph F. S. Fernando, Chao Zhang, Liangzhi Kou, Konstantin L. Firestein, Dmitri V. Golberg   +6 more
wiley   +1 more source

miR-133b Downregulation Reduces Vulnerable Plaque Formation in Mice with AS through Inhibiting Macrophage Immune Responses

Molecular Therapy: Nucleic Acids, 2019
Atherosclerosis (AS) is a chronic inflammatory disease characterized by accumulating deposition of lipids in the arterial intima. Notably, macrophages participate centrally in the pathogenesis of this deadly disease.
Cheng-Gen Zheng, Bing-Yu Chen, Ren-Hua Sun, Xiao-Zhou Mou, Fang Han, Qian Li, Hai-Jun Huang, Jing-Quan Liu, Yue-Xing Tu   +8 more
doaj   +1 more source