Results 171 to 180 of about 93,970 (258)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

WSGC@FA@PEG/PEI-SPIONs Mitigate Chemoresistance in Gastric Adenocarcinoma by Modulating the Notch Signaling Pathway and Mitophagy. [PDF]

Adv Sci (Weinh)
Song D, Liu Q, Yan Z, Wang Q, Su M, Zhang H, Shi L, Fan Y, Zhang Q, Yang H, Zhang D.   +10 more
europepmc   +1 more source

Oocyte–cumulus cell interaction: a key factor in early embryo development

Biological Reviews, EarlyView.
ABSTRACT The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.
Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero   +2 more
wiley   +1 more source

Radiation-Induced EMT of Adipose-Derived Stem Cells in 3D Organotypic Culture via Notch Signaling Pathway. [PDF]

Biology (Basel)
Choi SJ, Kim M, Chung KT, Son TG.
europepmc   +1 more source

From Material Tensions to Organizational Paradoxes: How Manufacturers Cope With the Limits of Circular Product Design

Business Strategy and the Environment, EarlyView.
ABSTRACT Circular product design (CPD) is central to advancing the circular economy by enabling the narrowing, slowing, and closing of resource flows. Yet, its implementation remains persistently challenging for firms. Prior research has largely framed these challenges as discrete barriers, overlooking the structural contradictions embedded in CPD ...
Vanessa Robertson, Nelly Rahimy, Suleika Bort   +2 more
wiley   +1 more source

Overexpression of <i>PPM1G</i> promotes cell metabolism and activates the NOTCH signaling pathway in lung adenocarcinoma. [PDF]

Transl Lung Cancer Res
Xi G, Zhang C, Yu C, Wang Y, Fu J, Qi H, Suda K, Wu G.   +7 more
europepmc   +1 more source

Noise‐Blocking Interfacial Lamination of Small‐Molecule Acceptors for Enhanced Signal Clarity in Organic Photodetectors

Carbon Energy, EarlyView.
The structural design strategy employing the Y6‐BO interfacial lamination suppresses dark current by limiting solvent‐induced interfacial damage through the formation of uniformly arranged interfaces while optimizing charge transport to achieve superior detectivity.
Jihyun Lim, Hyunguk Park, Woongsik Jang, Jae Hyun Jeong, Dong Hwan Wang   +4 more
wiley   +1 more source

[Retracted] Slit2 suppresses endothelial cell proliferation and migration by inhibiting the VEGF‑Notch signaling pathway. [PDF]

Mol Med Rep
Li GJ, Yang Y, Yang GK, Wan J, Cui DL, Ma ZH, Du LJ, Zhang GM.   +7 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source