Results 231 to 240 of about 156,496 (347)

Radiation-Induced EMT of Adipose-Derived Stem Cells in 3D Organotypic Culture via Notch Signaling Pathway. [PDF]

Biology (Basel)
Choi SJ, Kim M, Chung KT, Son TG.
europepmc   +1 more source

Inhibition of γ-Secretase Cleavage in the Notch Signaling Pathway Blocks HSV-2-Induced Type I and Type II Interferon Production

, 2010
Alexandra Svensson, Emely Jäkärä, Andrey Shestakov, Kristina Eriksson   +3 more
openalex   +2 more sources

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Overexpression of <i>PPM1G</i> promotes cell metabolism and activates the NOTCH signaling pathway in lung adenocarcinoma. [PDF]

Transl Lung Cancer Res
Xi G, Zhang C, Yu C, Wang Y, Fu J, Qi H, Suda K, Wu G.   +7 more
europepmc   +1 more source

Exploring the mechanism of &lt;italic&gt;Bufei Tongbi Decoction&lt;/italic&gt; (补肺通痹汤) in treating SLE-ILD based on the Notch signaling pathway and Th17/Treg balance [PDF]

Shu-Jing Wu, Huan Li, Z. Z. Zhao, Chih-Cheng Lu, Qin Li, Bitao Wang, Xueqin Zhou, Yan Li, Shuangya Li   +8 more
openalex   +1 more source

CS-37 * DUAL FUNCTIONS OF EFEMP1 IN MALIGNANT GLIOMA IN RESPECT TO REGULATION OF EGFR AND NOTCH SIGNALING PATHWAYS [PDF]

, 2014
Y.-H. Zhou, Yunjie Hu, Chao Ke, Ning Ru, Liping Yu, Eric R. Siegel, Mark E. Linskey   +6 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Effects of Probiotic-Fermented Deer Bone Water Extract on Immune Regulation and Gut Microbiota in Rheumatoid Arthritis via the NOTCH Signaling Pathway. [PDF]

Foods
Ma J, Jiang Y, Teng Y, Ren T, Xing Y, Li A, He Z, Chen W, Zong Y, Du R.   +9 more
europepmc   +1 more source