Results 201 to 210 of about 75,809 (268)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Ear tissue as a diagnostic sample for pestivirus detection in semi-domesticated Eurasian tundra reindeer (<i>Rangifer tarandus tarandus</i>) in Norway. [PDF]

open access: yesFront Microbiol
Malmström E   +7 more
europepmc   +1 more source

Notch [PDF]

open access: yesScience-Business eXchange, 2013
openaire   +1 more source

Decoding Trap States in Working 2D Perovskite Multi‐Functional Devices

open access: yesAdvanced Science, EarlyView.
Illustration of the photoluminescence spectrum and energy‐level landscape governing trap‐mediated carrier dynamics in 2D F‐PEAI photodetectors. A novel approach capturing dynamic trap occupation and retrapping in devices under operating conditions, directly links defect energetics to carrier transport and enhanced photoresponse in multifunctional ...
Ioannis Leontis   +8 more
wiley   +1 more source

Vortex Ratchet Effect in a NbC Strip With a Periodic Edge Indentation. [PDF]

open access: yesSmall Methods
Porrati F   +4 more
europepmc   +1 more source

Multifunctional E‐Tattoos Based on Electrospun PVBVA Fibers Coated with Ti3C2Tx MXene for Energy Harvesting, Energy Storage, and Biometric Sensing

open access: yesAdvanced Science, EarlyView.
This study explores a novel E‐tattoo made from PVBVA fibers coated with Ti3C2Tx MXene. The device is designed to harvest energy directly from the human body, providing power for itself. The research demonstrates the E‐tattoo's capability for charge storage and its potential for health monitoring through integrated ECG and EMG sensing, all within a ...
Ajay Pratap   +16 more
wiley   +1 more source

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