Results 61 to 70 of about 26,639 (292)
The Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2007 Research works regarding crack opening stresses covering various types of Mode I cracks initiated and growing in notches under cyclic loading are shown. A large number of parameters influence the crack opening behavior, i.e. material, crack length, notch
Alexander SAVAIDIS +3 more
doaj
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The influence of Notches on Domain Dynamics in Ferroelectric Nanowires [PDF]
, 2010 The extent to which notches inhibit axial switching of polarization in ferroelectric nanowires was investigated by monitoring the switching behavior of single crystal BaTiO(3) wires before and after patterning triangular notches along their lengths ...
S. C. Haire +13 more
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
A Hybrid Double Zero MVDR Beamformer That is Universal Over the Number of Second Order Notches
IEEE AccessIn a dynamic environment, close-range and fast-moving interferers transit the resolution cells rapidly, challenging the minimum variance distortionless response (MVDR) beamformer’s ability to place accurate notches in each interferer’s ...
Savas Erdim, John R. Buck
doaj +1 more source
Frontiers in Neuroscience, 2014 The interaction of sound waves with the human pinna introduces high-frequency notches (5-10 kHz) in the stimulus spectrum that are thought to be useful for vertical sound localization.
Ana eAlves-Pinto +2 more
doaj +1 more source
On the Stress Concentration in Multiple Notches
, 1962 The two-dimensional photoelastic investigation has been made on the effect of plate width, pitch, and depth of notch on the stress-concentration factor in a finite plate, which is for the single and multiple notches of any depth, under pure bending. Thus
Kunio Nishioka, Nobuyoshi Hisamitsu
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source