Results 61 to 70 of about 23,253 (298)

Revisiting classical concepts of Linear Elastic Fracture Mechanics - Part III: The stress field in a double-edge notched finite strip by means of the �stress-neutralization� technique

open access: yesFracture and Structural Integrity
This is the third part of a short series of paper, revisiting some classical concepts of Linear Elastic Fracture Mechanics. Based on the solution for the single edge notched strip, discussed in Part-II, the present study deals with the stress field ...
Christos F. Markides   +1 more
doaj   +3 more sources

Experimental and Theoretical Investigations on Mode I Crack Propagation in Notches under Cyclic Loading

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2007
Research works regarding crack opening stresses covering various types of Mode I cracks initiated and growing in notches under cyclic loading are shown. A large number of parameters influence the crack opening behavior, i.e. material, crack length, notch
Alexander SAVAIDIS   +3 more
doaj  

Notch Effect on Plastic Deformation of Metallic Glass: A Numerical Study by Revised Free-Volume Theory

open access: yesAdvances in Materials Science and Engineering, 2020
By means of a revised free-volume theory, the notch effect on metallic glass was systematically investigated by the numerical method. Simulations on specimens without notches demonstrated that the parameters being determined in this work could reasonably
J. F. Yan   +4 more
doaj   +1 more source

Chinese international students' experience of studying online in New Zealand.

open access: yes, 2011
Reasons distance students seek online study options include pursuing subjects of interest, taking subjects not available to them locally, or gaining a qualification from an institution of specialisation or reputation.
Cong, Yan   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Experimental Study of Forced- Convection from Horizontal Rectangular Fins Array into Air Duct

open access: yesAl-Khawarizmi Engineering Journal, 2019
In this work, an experimental study has been done to expect the heat characteristics and performance of the forced-convection from a heated horizontal rectangular fins array to air inside a rectangular cross-section duct.
Saad Najeeb Shehab
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Recent Advances in the Analytical Stress Field Solutions for Radiused Notches in Orthotropic Solids [PDF]

open access: yes, 2023
The main aim of this work is to provide a brief overview of the analytical solutions available to describe the in-plane and out-of-plane stress fields in orthotropic solids with radiused notches.
pastrello matteo   +2 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Notch one for activating NOTCH [PDF]

open access: yesScience-Business eXchange, 2011
Vanderbilt researchers have identified downregulation of NOTCH signaling as a mechanism tumors use to evade the immune system, suggesting that restoring activation of the pathway could improve cancer immunotherapy. Researchers have been split on whether it is better to up- or downregulate NOTCH.
openaire   +1 more source

Home - About - Disclaimer - Privacy