Results 31 to 40 of about 57,028 (302)
Descartes’ Ontological Proof: An Interpretation and Defense [PDF]
It is widely assumed among contemporary philosophers that Descartes’ version of ontological proof, among other weaknesses, makes an impossible and unjustified move from the mental world of concepts to the real world of things.
Judycki, Stanisław
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Nothingness is inconceivable, yet at the same time it is not inconceivable because it is actually referred to. I propose several accessibility relations to illustrate that nothingness is not an object at all.
Wai Lok Cheung
doaj +1 more source
Supernormalising Nothing from the Hyperbolic Nihil to the Ordinary Supernothing
This essay connects the mystical concept of “supernothing” with Bergson’s notion of the image of nothingness as a movement in the making. I do this also with respect to the film The Empty Man (David Prior, 2020) – which explicitly cites Gorgias’s four ...
Ó Maoilearca John
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One characteristic of the English language is its extensive use of affixes, and of suffixes in particular. Indeed, a dictionary count shows that some 45 per cent of the words listed are suffixed, including 2 per cent that are double-suffixed ...
Brooke, Maxey
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This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Review: The Powers of the Universe by Brian Swimme [PDF]
This essay presents a review on Brian Swimme’s 3-DVD set of lecture series in the interdisciplinary field of philosophy, cosmology and consciousness. In the eleven 45-minute episodes of a systematic 9-hour immersive program, a set of 12 intercorrelated ...
ma, Z. G.
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Existence and Negativity: The Relevance of the Patočka–Bergson Controversy over Nothingness
In in the second half of the 1940s, Jan Patočka emphasized the essentially negative character of human existence. He thus found himself in the neighborhood of Sartre’s existentialism, Heidegger’s philosophy of being, and Hegel’s dialectic, and at the ...
Jakub Čapek
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We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

