Results 41 to 50 of about 1,456 (259)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Run away illness where a rooster does not sing: No-life and nothingness in our folk fables [PDF]
In fables, verbal messages meant for curing, illness is never sent into underworld, nor is it wished for its death. After the analysis, the author concludes the reason for this attitude is in the understanding of the underworld: according to this view ...
Đapović Lasta
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The category of Nothingness as a factor in the aesthetics and poetics of modernist literature
The article defines the specifics of the influence of ideas about Nothingness on the artistic philosophy and aesthetics of modernism. It is stated that the feeling of the "liminal" time created an ambiguous perception of the world: the mystical fear of ...
Roman G. Zhitko
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Artistically Man Dwells: Advenant as an Actor in the Philosophy of Claude Romano
The study interprets the event hermeneutics of the French phenomenologist Claude Romano, which he postulated in the publications Event and World, Event and Time and There Is, through the prism of artistic experience.
Marcel Šedo
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Mind As Knower of Forms, And Awareness as The Knower of Being: A Phenomenological View
This article phenomenologically describes our ontological situation and our two modes of knowing. There is the knowing of mind as the knower of forms and the knower of awareness as the knower of Being. This paper links and integrates the tantric Dzogchen
Rudolph Bauer
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Nothingness at the Crossroads of Minor Canons
It is a mainstream assumption that Asian thinkers, and Chinese in particular, have devoted much of their speculative energies to investigating emptiness and nothingness, whereas these philosophical concepts would have been neglected (if not abhorred) in
Selusi Ambrogio
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

