Results 51 to 60 of about 1,450 (257)

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Wniknąć w nicość. Bernharda Weltego wykład o nadziei i rozpaczy [PDF]

open access: yesArgument, 2013
The thought of Bernhard Welte, a philosopher of religion from Fribourg, many times touched upon the subject of nothingness. This article aims at presenting the function he ascribed to the idea of nothingness in the context of constitutive experience ...
Joachim PIECUCH
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Inspiracje filozofią Sartre’a. Recenzja książki Sartre. L’Être et le néant. Nouvelles lectures, red. Jean-Marc Mouillie, Jean-Philippe Narboux, Paris: Les Belles Lettres, 2015

open access: yesAnaliza i Egzystencja, 2018
The article is scientific review a collection of articles "Sartre. L'Être et le néant. Nouvelles lectures "published in France in 2015. The authors set to analyze and interpret the selected threads of Sartre's conceptions developed in his work "Being and
Marta Chojnacka
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Beyond the Ontology–Cosmogony Dichotomy: Qi and the Worldview of the Laozi Zhigui

open access: yesReligions
This study examines the Laozi Zhigui—a key text of Han dynasty Huang-Lao thought—and reconstructs the categorical status of qi to reassess received primordial qi-centered cosmological interpretations and clarify the text’s distinctive worldview.
Hyunjung Oh
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Buddhism, Nothingness, and Pessimism

open access: yesAsian Studies
The present contribution excavates a pivotal shift in the history of European Buddhism. It outlines the conceptual-historical entanglements of “Buddhist nothingness” with nineteenth-century German philosophy from Schopenhauer to Nietzsche.
Eric S. Nelson
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Entre vanité et art poétique : l’esthétique du rien chez Graham Swift

open access: yesÉtudes Britanniques Contemporaines, 2012
As a metaphor of the disintegration into nothingness, the ashes in Last Orders bespeak the mere nothing of life (« it aint nothing at all ») and appear in numerous descriptions which can then be read as revisited vanitas paintings.
Christian Gutleben
doaj   +1 more source

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