Results 51 to 60 of about 57,028 (302)

Sitting at the Kantian Table of Nothingness

open access: yesJoLMA
This article appeals to the table of nothingness (Nichts) occurring within Kant’s Critique of Pure Reason [1781; 1787] (1998) to assess three recent accounts of nothingness – (Priest 2014), (Costantini 2020), and (Casati & Fujikawa 2019) - under ...
Simionato, Marco
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Zhuangzi and the Friendship of Non-Friendship

open access: yesAsian Studies
Bidding farewell to a friend is a moment of change, not in terms of the nature of the friendship, but the proximity of nothingness between oneself and another.
David Chai
doaj   +1 more source

Run away illness where a rooster does not sing: No-life and nothingness in our folk fables [PDF]

open access: yesGlasnik Etnografskog Instituta SANU, 2008
In fables, verbal messages meant for curing, illness is never sent into underworld, nor is it wished for its death. After the analysis, the author concludes the reason for this attitude is in the understanding of the underworld: according to this view ...
Đapović Lasta
doaj   +1 more source

Schopenhauer's World. The System of The World as Will and Presentation I [PDF]

open access: yes, 2017
in recent years, the research on Schopenhauer has shown a change in the interpretation of his main work, «The World as Will and Presentation», from (1) a normative and linear instruction which guides the reader from idealism to mysticism, pessimism and ...
Lemanski, Jens
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Out of nothing [PDF]

open access: yes, 2018
Graham Priest proposed an argument for the conclusion that \u2018nothing\u2019 occurs as a singular term and not as a quantifier in a sentence like (1) \u2018The cosmos came into existence out of nothing\u2019.
Sgaravatti, Daniele   +1 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Jean-Paul Sartre: Mystical Atheist or Mystical Antipathist? [PDF]

open access: yes, 2013
Jean-Paul Sartre is rarely discussed in the philosophy of religion. In 2009, however, Jerome Gellman broke the silence, publishing an article in which he argued that the source of Sartre’s atheism was neither philosophical nor existential, but mystical ...
Kirkpatrick, Kate
core  

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