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Surgical Pathology Clinics, 2021
This review provides an overview of the spectrum of tumors showing notochordal differentiation. This spectrum encompasses benign entities that are mostly discovered incidentally on imaging, reported as benign notochordal cell tumor, usually not requiring surgical intervention; slowly growing and histologically low-grade tumors referred to as ...
Roberto, Tirabosco +2 more
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This review provides an overview of the spectrum of tumors showing notochordal differentiation. This spectrum encompasses benign entities that are mostly discovered incidentally on imaging, reported as benign notochordal cell tumor, usually not requiring surgical intervention; slowly growing and histologically low-grade tumors referred to as ...
Roberto, Tirabosco +2 more
openaire +2 more sources
Apoptosis regulates notochord development in Xenopus [PDF]
Developmental Biology, 2007 The notochord is the defining characteristic of the chordate embryo and plays critical roles as a signaling center and as the primitive skeleton. In this study we show that early notochord development in Xenopus embryos is regulated by apoptosis. We find
Karen Symes, Marina Malikova
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Notochord Regulates Cardiac Lineage in Zebrafish Embryos [PDF]
Developmental Biology, 1998 We focus here upon regulation by the notochord of myocardial cell fate in zebrafish. Myocardial precursors, defined by lineage tracing in the living embryo, are in the lateral plate mesoderm adjacent to the notochord-prechordal plate junction ...
Allan Goldstein, M C Fishman
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Essential role of lysyl oxidases in notochord development [PDF]
Developmental Biology, 2007 Recent studies reveal a critical role for copper in the development of the zebrafish notochord, suggesting that specific cuproenzymes are required for the structural integrity of the notochord sheath. We now demonstrate that β-aminopropionitrile, a known
Jonathan D Gitlin, Stephen L Johnson
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Ascidian notochord morphogenesis [PDF]
Developmental Dynamics, 2007 AbstractThe development of the notochord involves a complex set of cellular behaviors. While these morphogenic behaviors are common to all chordates, the ascidian provides a particularly attractive experimental model because of its relative simplicity. In particular, all notochord morphogenesis in ascidians takes place with only 40 cells, as opposed to
William Smith
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The notochord: structure and functions
Cellular and Molecular Life Sciences, 2015The notochord is an embryonic midline structure common to all members of the phylum Chordata, providing both mechanical and signaling cues to the developing embryo. In vertebrates, the notochord arises from the dorsal organizer and it is critical for proper vertebrate development.
Diana Corallo, Paolo Bonaldo
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Developmental Biology, 2019 The elongation of embryo and tissue is a key morphogenetic event in embryogenesis and organogenesis. Notochord, a typical chordate organ, undergoes elongation to perform its regulatory roles and to form the structural support in the embryo. Notochord elongation is morphologically similar across all chordates, but ascidian has evolved distinct molecular
Yuan Gao, Bo Dong
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[Notochordal tumors: From notochord to chordoma].
Annales de pathologie, 2022The group of notochordal tumors consists of the benign notochordal cell tumor and the conventional, dedifferentiated and poorly differentiated chordomas in the fifth edition of the WHO classification of bone and soft tissue tumors. This update covers recent advances in the knowledge of the histogenesis and biology of these tumors and their implications
Jean-Marc, Guinebretière +1 more
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