The integrins of the urochordate provide novel insights into the molecular evolution of the vertebrate integrin family [PDF]
Background: Integrins are a functionally significant family of metazoan cell surface adhesion receptors. The receptors are dimers composed of an alpha and a beta chain.
Ewan, Richard +5 more
core +3 more sources
Asymmetric Fitness of Second-Generation Interspecific Hybrids Between Ciona robusta and Ciona intestinalis [PDF]
Abstract Reproductive isolation is central to speciation, but interspecific crosses between two closely related species can produce viable and fertile hybrids. Two different species of tunicates in the same ascidian genus, Ciona robusta and Ciona intestinalis, can produce hybrids.
Naoyuki Ohta +4 more
openaire +4 more sources
Ascidians, such as Ciona, are invertebrate chordates with simple embryonic body plans and small, relatively non-redundant genomes. Ciona genetics is in its infancy compared to many other model systems, but it provides a powerful method for studying this important vertebrate outgroup.
Michael T, Veeman +2 more
openaire +2 more sources
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Brown, Euan R. +2 more
core +1 more source
Barcoding of the cytochrome oxidase I (COI) indicates a recent introduction of Ciona savignyi into New Zealand and provides a rapid method for Ciona species discrimination [PDF]
Mitochondrial cytochrome oxidase I (COI) gene sequencing (DNA barcoding) of Ciona specimens from New Zealand (NZ) led to the first record of the solitary ascidian Ciona savignyi in the Southern Hemisphere. We sought to quantify C.
Cary, S. Craig +4 more
core +2 more sources
Germline transgenesis and insertional mutagenesis in the ascidian Ciona intestinalis [PDF]
Stable transgenesis is a splendid technique that is applicable to the creation of useful marker lines,enhancer/gene traps, and insertional mutagenesis.
Sasakura Yasunori, 笹倉 靖徳
core +1 more source
Monoaminergic modulation of photoreception in ascidian:evidence for a proto-hypothalamo-retinal territory [PDF]
Background : The retina of craniates/vertebrates has been proposed to derive from a photoreceptor prosencephalic territory in ancestral chordates, but the evolutionary origin of the different cell types making the retina is disputed.
Brown, Euan R +7 more
core +5 more sources
Neural crest lineage in the protovertebrate model Ciona [PDF]
Kouhei Oonuma +2 more
exaly +2 more sources
The calcium ion (Ca2+) is an important second messenger, and a rapid increase in Ca2+ level (Ca2+ transient) is involved in various aspects of embryogenesis. Although Ca2+ transients play an important role in early developmental stages, little is known about their dynamics throughout embryogenesis.
Taichi, Akahoshi +2 more
openaire +2 more sources
A Manually Curated Gene Model Set for an Ascidian, Ciona robusta (Ciona intestinalis Type A) [PDF]
Gene/transcript model sets predicted from decoded genome sequences are an important resource for a wide range of biological studies. Accuracy of gene models is therefore critical for deducing accurate conclusions. Computationally predicted models are sometimes inconsistent with experimental data from cDNA clones and RNA-sequencing.
Yutaka, Satou +6 more
openaire +2 more sources

