Results 11 to 20 of about 3,878 (161)

CRISPR Knockouts in Ciona Embryos [PDF]

, 2018
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 has emerged as a revolutionary tool for fast and efficient targeted gene knockouts and genome editing in almost any organism. The laboratory model tunicate Ciona is no exception.
Gandhi, Shashank, Razy-Krajka, Florian, Christiaen, Lionel, Stolfi, Alberto   +3 more
openaire   +6 more sources

How Fast Is the Sessile Ciona? [PDF]

Comparative and Functional Genomics, 2009
Genomewide analyses of distances between orthologous gene pairs from the ascidian speciesCiona intestinalisandCiona savignyiwere compared with those of vertebrates. Combining this data with a detailed and careful use of vertebrate fossil records, we estimated the time of divergence between the two ascidians nearly 180 My.
Berná, Luisa, Alvarez-Valin, Fernando, D'Onofrio, Giuseppe   +2 more
openaire   +4 more sources

The nervous system of the adult ascidian Ciona intestinalis Type A (Ciona robusta): Insights from transgenic animal models. [PDF]

PLoS ONE, 2017
The nervous system of ascidians is an excellent model system to provide insights into the evolutionary process of the chordate nervous system due to their phylogenetic positions as the sister group of vertebrates.
Tomohiro Osugi, Yasunori Sasakura, Honoo Satake   +2 more
doaj   +2 more sources

Asymmetric Fitness of Second-Generation Interspecific Hybrids Between Ciona robusta and Ciona intestinalis

G3: Genes, Genomes, Genetics, 2020
Reproductive isolation is central to speciation, but interspecific crosses between two closely related species can produce viable and fertile hybrids.
Naoyuki Ohta, Nicole Kaplan, James Tyler Ng, Basile Jules Gravez, Lionel Christiaen   +4 more
doaj   +2 more sources

Ciona Genetics [PDF]

, 2011
Ascidians, such as Ciona, are invertebrate chordates with simple embryonic body plans and small, relatively non-redundant genomes. Ciona genetics is in its infancy compared to many other model systems, but it provides a powerful method for studying this important vertebrate outgroup.
Michael T, Veeman, Shota, Chiba, William C, Smith   +2 more
openaire   +2 more sources

Comparing the sensitivity of two cogeneric ascidian species to two plastic additives: Bisphenol A and the flame retardant tris(chloro-propyl)phosphate

The European Zoological Journal, 2022
Although sensitivity to pollutants is well known to be species specific, closely related species are often assumed to respond similarly to them. We tested this assumption, comparing the sensitivity of Ciona intestinalis and Ciona robusta to two common ...
S. Mercurio, S. Messinetti, B. Barzaghi, R. Pennati   +3 more
doaj   +1 more source

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]

, 2013
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington’s disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Idris, Mohammed M, Thorndyke, Michael C.,, Brown, Euan R., Brown, Euan R.; id_orcid, Idris, Mohammed M., Thorndyke, Michael C   +5 more
core   +1 more source

Natural variation of model mutant phenotypes in Ciona intestinalis [PDF]

, 2008
The study of ascidians (Chordata, Tunicata) has made a considerable contribution to our understanding of the origin and evolution of basal chordates. To provide further information to support forward genetics in Ciona intestinalis, we used a combination ...
Annamaria Locascio, Sordino, Paolo, D'Ambrosio Palmira, Ristoratore, Filomena, Monia Teresa Russo, Maiella, Sylvie, Russo, Monia Teresa, Spagnuolo Antonietta, Locascio, Annamaria, Branno Margherita, Sorrenti Gerarda, Daniele, Paola, Spagnuolo, Antonietta, Filomena Ristoratore, Antonietta Spagnuolo, Salvatore D'Aniello, Sylvie Maiella, D'Ambrosio, Palmira, Ristoratore Filomena, Zanetti, Laura, Branno, Margherita, Enrico D'Aniello, D'Aniello Enrico, Russo Monia Teresa, Margherita Branno, Miraglia Valentina, Squarzoni Paola, Zanetti Laura, Squarzoni, Paola, Tarallo, Raffaella, Luigi Caputi, Andreakis, Nikos, Sordino Paolo, Paola Daniele, Caputi, Luigi, Tarallo Raffaella, D'Aniello Salvatore, Laura Zanetti, Miraglia, Valentina, Paola Cirino, Cirino Paola, Locascio Annamaria, Christian Alfano, D'Aniello, Enrico, Gerarda Sorrenti, Leccia Nicola I., Brown, Euan R; id_orcid, Valentina Miraglia, Palmira D'Ambrosio, Daniele Paola, Euan R Brown, Caputi Luigi, Paolo Sordino, Nicola I Leccia, Leccia, Nicola I, Raffaella Tarallo, D'Aniello, Salvatore, Andreakis Nikos, Brown Euan R., Cirino, Paola, Alfano, Christian, Alfano Christian, Nikos Andreakis, Paola Squarzoni, Lucio Cariello, Sorrenti, Gerarda, Cariello Lucio, Cariello, Lucio, Maiella Sylvie   +68 more
core   +2 more sources

Barcoding of the cytochrome oxidase I (COI) indicates a recent introduction of Ciona savignyi into New Zealand and provides a rapid method for Ciona species discrimination [PDF]

, 2012
Mitochondrial cytochrome oxidase I (COI) gene sequencing (DNA barcoding) of Ciona specimens from New Zealand (NZ) led to the first record of the solitary ascidian Ciona savignyi in the Southern Hemisphere. We sought to quantify C.
Thia, Joshua, Smith, Kirsty Fiona, Fidler, Andrew E., Smith, Kirsty F., Cary, S. Craig, Gemmill, Chrissen E. C., Gemmill, Chrissen E.C.   +6 more
core   +1 more source

Developmental Table and Three-Dimensional Embryological Image Resource of the Ascidian Ascidiella aspersa

Frontiers in Cell and Developmental Biology, 2021
Ascidiella aspersa is an ascidian in the class of chordates—the closest relatives of vertebrates. A. aspersa is a potential model organism for bio-imaging studies due to its extremely transparent embryos as well as is a globally distributed cosmopolitan ...
Haruka M. Funakoshi, Takumi T. Shito, Kotaro Oka, Kotaro Oka, Kotaro Oka, Kohji Hotta   +5 more
doaj   +1 more source