The repertoire of G protein-coupled receptors in the sea squirt
BMC Evolutionary Biology, 2008 Background G protein-coupled receptors (GPCRs) constitute a large family of integral transmembrane receptor proteins that play a central role in signal transduction in eukaryotes. The genome of the protochordate Ciona intestinalis has a compact size with
Manoj Narayanan +2 more
doaj +1 more source
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
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The Cis-Regulatory Code for Kelch-like 21/30 Specific Expression in Ciona robusta Sensory Organs
Frontiers in Cell and Developmental Biology, 2020 The tunicate Ciona robusta is an emerging model system to study the evolution of the nervous system. Due to their small embryos and compact genomes, tunicates, like Ciona robusta, have great potential to comprehend genetic circuitry underlying cell ...
Ugo Coppola +4 more
doaj +1 more source
eLife, 2022 Gene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential gene regulatory network that ...
Yushi Wu +8 more
doaj +1 more source
How Fast Is the Sessile Ciona? [PDF]
Comparative and Functional Genomics, 2009 Genomewide analyses of distances between orthologous gene pairs from the ascidian speciesCiona intestinalisandCiona savignyiwere compared with those of vertebrates. Combining this data with a detailed and careful use of vertebrate fossil records, we estimated the time of divergence between the two ascidians nearly 180 My.
Berná, Luisa +2 more
openaire +2 more sources
Viruses, 2018 Phages (viruses that infect bacteria) play important roles in the gut ecosystem through infection of bacterial hosts, yet the gut virome remains poorly characterized.
Alexandria Creasy +4 more
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TCF/Lef regulates the Gsx ParaHox gene in central nervous system development in chordates [PDF]
, 2016 This research was supported by a BBSRC-DTG studentship to M.G.G, and Clarendon, ORS and EPA Cephalosporin scholarships to P.W.O.Background The ParaHox genes play an integral role in the anterior-posterior (A-P) patterning of the nervous system and gut of
Ferrier, David Ellard Keith +2 more
core +1 more source
Prophage regulation of <i>Shewanella fidelis</i> 3313 motility and biofilm formation with implications for gut colonization dynamics in <i>Ciona robusta</i>. [PDF]
ElifeLysogens, bacteria with one or more viruses (prophages) integrated into their genomes, are abundant in the gut of animals. Prophages often influence bacterial traits; however, the influence of prophages on the gut microbiota–host immune axis in animals ...
Natarajan O +12 more
europepmc +2 more sources
Outgroup, alignment and modelling improvements indicate that two TNFSF13-like genes existed in the vertebrate ancestor [PDF]
, 2017 Peer reviewedPublisher ...
Dooley, Helen +2 more
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Bifurcations in valveless pumping techniques from a coupled fluid-structure-electrophysiology model in heart development [PDF]
, 2017 We explore an embryonic heart model that couples electrophysiology and muscle-force generation to flow induced using a $2D$ fluid-structure interaction framework based on the immersed boundary method.
Battista, Nicholas A., Miller, Laura A.
core +2 more sources