Results 101 to 110 of about 210,426 (300)

LA INMIGRACIÓN: UN FENÓMENO NATURAL, CONVERTIDO EN PROBLEMA

open access: yesDidáctica Geográfica, 2011
RESUMEN: Una de les características que singularizan el siglo XXI es el fenómeno de la interculturalidad en un mundo globalizado que ha roto fronteras a través de las nuevas tecnologías y las comunicaciones, pero donde al mismo tiempo los países más ...
Enric Ramiro i Roca
doaj  

Learning in an age of digital networks

open access: yes, 2010
The final years of the twentieth century and early years of the twenty first century have been marked by the rapid rise of digital and networked technologies.
Jones, Chris, Sclater, Niall
core  

Hamster leukemia virus: lack of endogenous DNA synthesis and unique structure of its DNA polymerase [PDF]

open access: yes, 1974
Infectious hamster leukemia virus (HaLV) contains a DNA polymerase different from those of murine and avian viruses. No endogenous reaction directed by the 60 to 70S RNA of HaLV could be demonstrated in detergenttreated HaLV virions, nor could the ...
Baltimore, David   +3 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Red, White and Bicycle: RVA, France and the Bike Race, Blog 2 [PDF]

open access: yes, 2015
Student blog posts from the Great VCU Bike Race ...
Mack, Jamie
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

LA INMIGRACIÓN: UN FENÓMENO NATURAL, CONVERTIDO EN PROBLEMA

open access: yesDidáctica Geográfica, 2009
RESUMEN:Una de les características que singularizan el siglo XXI es el fenómeno de la interculturalidad en un mundo globalizado que ha roto fronteras a través de las nuevas tecnologías y las comunicaciones, pero donde al mismo tiempo los países más ...
Enric Ramiro i Roca
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Etude de l’activité pouzzolanique d’une roche andésitique en Algérie Study of the pozzolanic activity of an andesitic rock in Algeria

open access: yesMATEC Web of Conferences, 2012
Ce travail s’inscrit dans le cadre de l’accord programme Tassili N° 09 MDU 773 entre le Laboratoire de Physicochimie des Matériaux, USTO-Oran et le Laboratoire des Matériaux et Durabilité des Constructions (LMDC), INSA-UPS-Toulouse, France.
Clastres P.   +3 more
doaj   +1 more source

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