Results 51 to 60 of about 122,049 (241)
The crocodile icefish, Chionobathyscus dewitti, belonging to the family Channichthyidae, is an endemic species of the Southern Ocean. The study of its biological features and genetics is challenging as the fish inhabits the deep sea around Antarctic ...
Jinmu Kim +7 more
doaj +1 more source
The complete chloroplast genome of Meconopsis pinnatifolia and Meconopsis paniculata
Two species, Meconopsis pinnatifolia and Meconopsis paniculate, were newly collected from Qinghai-Tibet plateau (QTP), China at altitudes of 3,944m and 3,632m respectively in 2022.
Shuqi Zhao (16946760)
core +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
DAP-seq was used to identify transcription factor binding sites for EgrMYB1 (Eucgr.G01774), EgrMYB2 (Eucgr.G03385), EgrMYB122 (Eucgr.J01601) and EgrMYB135 (Eucgr.K02297) transcription factors. Sequencing was carried out on an Illumina NovaSeq 6000 (PE150)
Lazarus Takawira (17547396)
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Pterobryopsis orientalis (Müll. Hal.) M. Fleisch. 1917, a subtropical moss from the family Pterobryaceae, is native to the western Himalaya. In this study, the complete chloroplast genome of P.
Wei Han +4 more
doaj +1 more source
International audienceThe draft genome sequences of 1AS11 T , 1AS12 and 1AS13 were deposited under the accession numbers JAPCZM000000000, JAPCZN000000000 and JAPCZO000000000, respectively.The Illumina NovaSeq 6000 raw reads are deposited in the Sequence ...
Ellouze, Walid +29 more
core +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Seawater is often applied to improve crop quality by supplying minerals to the crop. Due to high salt concentration of seawater, one of key factors for successful utilization of seawater in agriculture would be optimal dilution ratios, which can be ...
Dewi Komang Anggita +3 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source

