Acta Paediatrica, EarlyView.ABSTRACT Aim To examine the prevalence of severe psychiatric morbidity among gender‐referred adolescents, focusing on gender differences and outcomes related to medical gender reassignment. Methods Finnish nationwide cohort of all under‐23‐year‐old gender‐referred individuals between 1996 and 2019 (n = 2 083) and 16 643 matched controls.
Sami‐Matti Ruuska +3 more
wiley +1 more source
Knowledge, attitudes, and practices of Chinese college students towards novel psychoactive substances. [PDF]
BMC Public HealthLu L +6 more
europepmc +1 more source
The Role of Dopamine in the Stimulant Characteristics of Novel Psychoactive Substances (NPS)-Neurobiological and Computational Assessment Using the Case of Desoxypipradrol (2-DPMP). [PDF]
Front Pharmacol, 2020 Loi B +4 more
europepmc +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
Novel Psychoactive Substances in Custodial Settings: A Mixed Method Investigation on the Experiences of People in Prison and Professionals Working With Them. [PDF]
Front Psychiatry, 2020 Corazza O +11 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr +10 more
wiley +1 more source
Development and validation of a questionnaire to assess knowledge, attitudes, and practices regarding the addictive and detrimental effects of novel psychoactive substances among university students. [PDF]
BMC Public HealthLu L, Deng J, Li F, Zhu X.
europepmc +1 more source
Safety pharmacology of acute mescaline administration in healthy participants
British Journal of Clinical Pharmacology, EarlyView.Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber +4 more
wiley +1 more source
Using sleep to enhance exposure treatment for anxious children: A pilot study
British Journal of Clinical Psychology, EarlyView.Abstract Objectives: Exposure therapy is a well‐established treatment for anxiety disorders in children; however, many young people do not fully respond to treatment. Advances in strategies to enhance extinction learning from exposure therapy are urgently needed.
Ella L. Oar +4 more
wiley +1 more source
Predictors of depressive symptoms and depression in women with previous pregnancy loss
British Journal of Clinical Psychology, EarlyView.Abstract Objectives Depressive symptoms are common in females after pregnancy loss. However, research on risk factors for developing a clinical depressive episode remains limited and with inconsistent findings. This study examined the association of demographic variables (like age), pregnancy‐related factors (like number of miscarriages or stillbirths),
Sarah M. Quaatz +6 more
wiley +1 more source