Novel Method to Flag Cardiac Implantable Device Infections by Integrating Text Mining With Structured Data in the Veterans Health Administration’s Electronic Medical Record [PDF]
, 2020 Hillary J. Mull +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A novel structure associated with aging is augmented in the DPP6-KO mouse brain. [PDF]
Acta Neuropathol Commun, 2020 Lin L +4 more
europepmc +1 more source
Dual targeting of 3CLpro and PLpro of SARS-CoV-2: A novel structure-based design approach to treat COVID-19. [PDF]
Curr Res Struct Biol, 2021 Rajpoot S, Alagumuthu M, Baig MS.
europepmc +1 more source
Strength Analysis of a Novel High-Pressure Die with Double-Layered Split Structure [PDF]
, 2018 Zhuo Yi +5 more
openalex +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A novel structure for online surgical undergraduate teaching during the COVID-19 pandemic. [PDF]
BMC Med Educ, 2020 Chandrasinghe PC +8 more
europepmc +1 more source
The crystal structure of a novel mammalian lectin Ym1 suggests a saccharide binding site [PDF]
, 2002 Yi Sun +4 more
openalex +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source