Results 41 to 50 of about 272,983 (311)

Even Simple Processes of π-calculus are Hard for Analysis

open access: yesМоделирование и анализ информационных систем, 2018
Mathematical models of distributed computations, based on the calculus of mobile processes (π-calculus) are widely used for checking the information security properties of cryptographic protocols.
Marat M. Abbas, Vladimir A. Zakharov
doaj   +1 more source

Instruction Sequence Based Non-uniform Complexity Classes [PDF]

open access: yesScientific Annals of Computer Science, 2014
We present an approach to non-uniform complexity in which single-pass instruction sequences play a key part, and answer various questions that arise from this approach. We introduce several kinds of non-uniform complexity classes.
J.A. Bergstra, C.A. Middelburg
doaj   +1 more source

Vertex order with optimal number of adjacent predecessors [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2020
In this paper, we study the complexity of the selection of a graph discretization order with a stepwise linear cost function. Finding such vertex ordering has been proved to be an essential step to solve discretizable distance geometry problems (DDGPs ...
Jérémy Omer, Tangi Migot
doaj   +1 more source

Tetravex is NP-complete

open access: yesInformation Processing Letters, 2006
Tetravex is a widely played one person computer game in which you are given $n^2$ unit tiles, each edge of which is labelled with a number. The objective is to place each tile within a $n$ by $n$ square such that all neighbouring edges are labelled with an identical number. Unfortunately, playing Tetravex is computationally hard.
Yasuhiko Takenaga, Toby Walsh
openaire   +3 more sources

The Internet Shopping Optimization Problem with Multiple Item Units (ISHOP-U): Formulation, Instances, NP-Completeness, and Evolutionary Optimization

open access: yesMathematics, 2022
In this work, we investigate the variant of the Internet Shopping Optimization Problem (ISHOP) that considers different item units. This variant is more challenging than the original problem. The original ISHOP is already known as a combinatorial NP-hard
Fernando Ornelas   +9 more
doaj   +1 more source

Separating NP-Completeness Notions under Strong Hypotheses

open access: yes, 2000
Lutz (1993, “Proceedings of the Eight Annual Conference on Structure in Complexity Theory,” pp. 158–175) proposed the study of the structure of the class NP=NTIME(poly) under the hypothesis that NP does not have p-measure 0 (with respect to Lutz's ...
Bentzien, Levke, Ambos-Spies, Klaus
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

NP-completeness of the Eulerian walk problem for a multiple graph

open access: yesМоделирование и анализ информационных систем
In this paper, we study undirected multiple graphs of any natural multiplicity $k>1$. There are edges of three types: ordinary edges, multiple edges and multi-edges. Each edge of the last two types is a union of $k$ linked edges, which connect 2 or $(k+1)
Alexander V. Smirnov
doaj   +1 more source

Tokenisation is NP-Complete

open access: yesProceedings of the 63rd Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
In this work, we prove the NP-completeness of two variants of tokenisation, defined here as the problem of compressing a dataset to at most 𝛿 symbols by either finding a vocabulary directly (_direct_ tokenisation), or selecting a sequence of merge operations (_bottom-up_ tokenisation).
Philip Whittington   +2 more
openaire   +3 more sources

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