Results 91 to 100 of about 114,500 (312)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

DIGITAL SUBSTATION COMPONENT SYSTEM "SMART GRID"

open access: yesElectrical engineering & Electromechanics, 2014
New production technologies of modern control systems have moved from the stage of research and experimentation into the stage of practical use. Modern communication standards for the exchange of information are developed and introduced. Digital devices,
V.I. Vasilchenko   +4 more
doaj  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

open access: yesAdvanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet   +13 more
wiley   +1 more source

A case of the complicated course of drug-resistant tuberculosis in a 14-year-old adolescent

open access: yesЯкутский медицинский журнал
The article presents a clinical case of drug-resistant tuberculosis in a teenager. The peculiarity of the clinical case is related to the fact that the teenager was deregistered for local tuberculosis was observed for local tuberculosis, but a year later
N. A. Gulyaeva   +4 more
doaj   +1 more source

After the NPC: Where does China go from here [PDF]

open access: yes
China’s National People’s Congress (NPC) and the Chinese People’s Political Consultative Conference (CPPCC) met for the respective annual sessions during March 5-10.
Godbole, Avinash
core  

Data Patient LMP VEGF NPC M. Yusuf

open access: yes, 2023
Data include numerous patients joining the NPC trial to show correlation between LMP 1 and VEGF towards NPC progression.
Artono Artono (15972664)   +5 more
core   +1 more source

Taking Stock: Assessing Animal Welfare in South African Captive Lion Tourism Venues

open access: yesAnimals
South Africa maintains thousands of captive lions and other felids in commercial captive wildlife facilities. Despite ongoing debate regarding the welfare implications of this industry, empirical assessments of welfare conditions remain limited.
Louise de Waal   +5 more
doaj   +1 more source

Novel Mutations in NPC1 are Associated with Pelizaeus-Merzbacher-Like Disease: A Case Report

open access: yesInternational Journal of General Medicine, 2021
Hongling Fu,1,2 Qiu Wang,2,3 Hanmin Liu1,2 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2Key Laboratory of Birth Defect and Related Diseases of Women and ...
Fu H, Wang Q, Liu H
doaj  

Transfer of Cholesterol by the NPC Team [PDF]

open access: yesCell Metabolism, 2010
The mechanisms of intracellular cholesterol transport are largely unknown. In this issue of Cell Metabolism, Wang et al. (2010) identify amino acid residues on the lumenal lysosomal protein Niemann-Pick C2 (NPC2) that are required for intralysosomal transfer of endocytosed cholesterol to membrane-bound NPC1 via a process that avoids movement of ...
openaire   +2 more sources

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