A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response. [PDF]
, 2018 The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes.
Cheng, Zhi +27 more
core +2 more sources
Actin assembly ruptures the nuclear envelope by prying the lamina away from nuclear pores and nuclear membranes in starfish oocytes. [PDF]
, 2020 The nucleus of oocytes (germinal vesicle) is unusually large and its nuclear envelope (NE) is densely packed with nuclear pore complexes (NPCs) stockpiled for embryonic development. We showed that breakdown of this specialized NE is mediated by an Arp2/3-
Avilov, I. +6 more
core +1 more source
Evolutionarily Conserved Sequence Features Regulate the Formation of the FG Network at the Center of the Nuclear Pore Complex. [PDF]
, 2015 The nuclear pore complex (NPC) is the portal for bidirectional transportation of cargos between the nucleus and the cytoplasm. While most of the structural elements of the NPC, i.e.
Lee, BL +3 more
core +2 more sources
Structure-function mapping of a heptameric module in the nuclear pore complex. [PDF]
, 2012 The nuclear pore complex (NPC) is a multiprotein assembly that serves as the sole mediator of nucleocytoplasmic exchange in eukaryotic cells. In this paper, we use an integrative approach to determine the structure of an essential component of the yeast ...
Chait, Brian T +10 more
core +2 more sources
Effect of the Weight Training Period on the Increase in the 100 Meter Run in Indonesian NPC Athletes
Kinestetik, 2022 The population and samples in this study were all 10 sprint athletes in the Indonesian National Paralympic Committee (NPC) 10 men. The sampling technique uses purposive samples, as it takes into account the characteristics of the sexes.
Nurhidayat Nurhidayat +4 more
doaj +1 more source
Linear cyclodextrin polymer prodrugs as novel yherapeutics for Niemann-Pick type C1 disorder [PDF]
, 2018 Niemann-Pick Type C1 disorder (NPC) is a rare lysosomal storage disease characterized by the accumulation of cholesterol in lysosomes. NPC has no FDA approved treatments yet, however 2-hydroxypropyl-β-cyclodextrin (HPβCD) has shown efficacy for treating ...
Aditya Kulkarni +8 more
core +1 more source
Co-culture of Adult Mesenchymal Stem Cells and Nucleus Pulposus Cells in Bilaminar Pellets for Intervertebral Disc Regeneration [PDF]
, 2009 Background: Our goal is to optimize stem cell-based tissue engineering strategies in the context of the intervertebral disc environment. We explored the benefits of co-culturing nucleus pulposus cells (NPC) and adult mesenchymal stem cells (MSC) using a ...
Allon, AA, Lotz, JC, Schneider, RA
core +2 more sources
miR-212-5p inhibits nasopharyngeal carcinoma progression by targeting METTL3
Open Medicine, 2022 This study was conducted to investigate the effect of microRNA-212-5p (miR-212-5p) on the proliferation and apoptosis of nasopharyngeal carcinoma (NPC) cells.
Zhou Hongyu, Zhang Nana
doaj +1 more source
Substantial gain enhancement for optical parametric amplification and oscillation in two-dimensional χ(2) nonlinear photonic crystals [PDF]
, 2008 We have analyzed optical parametric interaction in a 2D NPC. While in general the nonlinear coefficient is small compared to a 1D NPC, we show that at numerous orientations a multitude of reciprocal vectors contribute additively to enhance the gain in ...
Kung, A. H., Liu, Hsi-Chun
core +1 more source
Tailoring polypropylene properties by package of internal/external donor in Ziegler Natta catalysts [PDF]
Polyolefins JournalInsights have been developed into the influence of different structures, including bismethoxymethylfluorene (B) and 2,2-diisopropyl succinate (I), on both internal donor (ID) and external donor (ED) roles on the performance of MgCl2/ID/TiCl4.
Nona Ghasemi Hamedani +3 more
doaj +1 more source