Results 61 to 70 of about 114,500 (312)
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Ecology and Evolution, 2023 Abiotic factors are usually considered key drivers of species distribution at macro scales, while biotic interactions are mostly used at local scales.
Francesca Cosentino +3 more
doaj +1 more source
, 2011 Nasopharyngeal carcinoma (NPC) is prevalent in south-eastern Asia, particularly southern China, Singapore and Taiwan. The aim of this study was to identify the pivotal genes that may be altered during NPC progression.
郭源松;湯月碧;呂東盈;吳漢忠;林欽塘 +1 more
core +1 more source
Advanced Science, EarlyView.A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Advanced Science, EarlyView.Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
ADRs reported to NPC per year vs those not reported to NPC.
, 2023 ADRs reported to NPC per year vs those not reported to NPC.
Delese Mimi Darko (14172264) +9 more
core +1 more source
Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Calling for cross-sector engagement with traditional health practitioners in South Africa
Frontiers in Conservation ScienceTraditional health practitioners (THPs) are recognised for their roles in maintaining indigenous knowledge and cultural practices, and providing healthcare in local communities, however they have received less recognition as custodians of the environment.
Stephanie-Emmy Klarmann +2 more
doaj +1 more source
Application of renewable energy resources in a microgrid power system
The Journal of Engineering, 2019 In order to meet the power prerequisites of their citizens, many countries are heavily dependent on the utilization of fossil fuels for power generation. This has reduced the natural reserve of fossil fuels and caused a large percentage of greenhouse gas
Temitope Adefarati, Ramesh C. Bansal
doaj +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source