Results 101 to 110 of about 523 (110)

Using N‐Nitrosodiethanolamine (NDELA) and N‐Nitrosopiperidine (NPIP) Transgenic Rodent Gene Mutation Data and Quantum Mechanical Modeling to Derive Potency‐Based Acceptable Intakes for NDSRIs Lacking Robust Carcinogenicity Data

Environmental and Molecular Mutagenesis
ABSTRACTAcceptable intake (AI) limits for nitrosamine drug substance related impurities (NDSRIs) that lack carcinogenicity data could be estimated from mutagenic potency relative to anchor nitrosamines with carcinogenicity data. This approach integrates points of departure (PoDs) derived from in vivo mutagenicity studies with in silico predictions ...
Jason M. Roper, Troy R. Griffin, George E. Johnson, Jakub Kostal, Raphael Nudelman, Gregory R. Ott, Adelina Voutchkova‐Kostal, Valerie Niddam‐Hildesheim   +7 more
openaire   +1 more source

Priprema projekta ulaganja u zaštitu prirode Republike Hrvatske (NPIP projekt)

2009
Cilj projekta je napraviti procjenu projekata za izradu sustava ulaganja u zaštitu okoliša Republike Hrvatske za Svjetsku banku (i / ili druge donatore) i eventualnu provedbu. Nalazi uključuju ključne dokumente i izvještaje koji će sačinjavati projektni prijedlog za ulaganja u sustav zaštite prirode Republike Hrvatske kroz slijedećih pet godina u ...
openaire   +2 more sources

Correction to: A comprehensive review on various carcinogenic aspects of N-nitrosopiperidine (NPIP)

Phytochemistry Reviews
Priya Chaudhary, Devendra Singh, Pracheta Janmeda   +2 more
openaire   +1 more source

Nitrosamine formation in a semi-dry fermented sausage: Effects of nitrite, ascorbate and starter culture and role of cooking

Meat Science, 2020
Mükerrem Kaya, Güzin Kaban Kaban G, Selen Sallan   +2 more
exaly  

Factors influencing the microsome- and mitochondria-catalyzed in vitro binding of diethylnitrosamine and N-nitrosopiperidine to deoxyribonucleic acid

Biochemical Pharmacology, 1979
J C Arcos, Joseph C Arcos, Mary F Argus
exaly  

Comparative metabolism of N-nitrosopiperidine and N-nitrosopyrrolidine by rat liver and esophageal microsomes and cytochrome P450 2A3

Carcinogenesis, 2003
Stephen Hecht, Mingyao Wang, Hecht Stephen S   +2 more
exaly  

Comparative genotoxicity of nitrosamine drinking water disinfection byproducts in Salmonella and mammalian cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2012
Michael Plewa, Elizabeth Wagner, William Mitch   +2 more
exaly  

Protective effects of isothiocyanates alone or in combination with vitamin C towardsN-nitrosodibutylamine orN-nitrosopiperidine-induced oxidative DNA damage in the single-cell gel electrophoresis (SCGE)/HepG2 assay

Journal of Applied Toxicology, 2008
exaly  

Organosulfur compounds alone or in combination with vitamin C protect towards N-nitrosopiperidine- and N-nitrosodibutylamine-induced oxidative DNA damage in HepG2 cells

Chemico-Biological Interactions, 2008
exaly  

Using N‐Nitrosodiethanolamine (NDELA) and N‐Nitrosopiperidine (NPIP) Transgenic Rodent Gene Mutation Data and Quantum Mechanical Modeling to Derive Potency‐Based Acceptable Intakes for NDSRIs Lacking Robust Carcinogenicity Data [PDF]

openaire