Results 121 to 130 of about 52,027 (252)

Investigating the Ligament Involvement in High-Energy and Polytraumatic Multiligament Knee Injuries Compared With Low-Energy or Isolated Injuries

open access: yesOrthopaedic Journal of Sports Medicine
Background: Multiligament knee injuries (MLKIs) due to high-energy (HE) or polytraumatic (PT) mechanisms result in worse patient outcomes after surgery versus low-energy (LE) or nonpolytraumatic (NPT) mechanisms.
Collin D.R. Hunter BS   +7 more
doaj   +1 more source

Nano-Pulse Treatment Overcomes the Immunosuppressive Tumor Microenvironment to Elicit In Situ Vaccination Protection against Breast Cancer

open access: yesVaccines
We previously reported that nano-pulse treatment (NPT), a pulsed power technology, resulted in 4T1-luc mammary tumor elimination and a strong in situ vaccination, thereby completely protecting tumor-free animals against a second live tumor challenge. The
Anthony Nanajian   +6 more
doaj   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

open access: yesAdvanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran   +10 more
wiley   +1 more source

When Mechanics Rewrites Chemistry: Divergent Pathways of Hardening and Softening in High Strength Al‐Alloys

open access: yesAdvanced Science, EarlyView.
Mechanics reshapes chemistry: plastic flow actively governs two divergent, atomic‐scale mechanochemical pathways that tailor strain localization and ductility in high‐strength 7xxx Al alloys. Rather than relying on static structures, deformation dynamically reinforces the solution‐treated state via clustering, yet destabilizes the peak‐aged condition ...
Huan Zhao   +9 more
wiley   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

TRANS.NPT [NPT Transcript]

open access: yes, 2000
Disk image of a floppy disk containing one text file (SEATRAN.NPT) of a letter from Paul Leventhal to Hasmy Agam of Malaysia (Ambassador to the U.N.), requesting that Malaysia raise the issue of safety and environmental risks associated with maritime ...
Leventhal, Paul   +1 more
core   +1 more source

Resolving Oxidative and Corrosive Calendar‐Aging via Electrolyte Engineering for Stable Lithium Metal Batteries

open access: yesAdvanced Energy Materials, EarlyView.
A weakly solvating ether solvent, 1,2‐dimethoxypropane (DMP), is proposed for use in localized high‐concentration electrolytes (LHCEs) for lithium metal batteries (LMBs). These DMP‐based LHCEs simultaneously suppress lithium metal corrosion and cathode degradation—two interrelated processes that accelerate calendar aging of LMBs.
Jisub Kim   +14 more
wiley   +1 more source

Insights into the Degradation Mechanism of Aqueous LiMn2O4–Cathode Interfaces by Computational Vibrational Spectroscopy

open access: yesAngewandte Chemie, EarlyView.
LiMn2O4${\rm LiMn}_2{\rm O}_4$ is of high interest for sustainable energy storage and conversion. Its mixed‐valence Mn3+${\rm Mn}^{3+}$/Mn4+${\text{Mn}}^{4+}$ structure drives site‐specific behavior at aqueous interfaces, featuring proton‐generating Mn4+${\text{Mn}}^{4+}$ centers and electron‐rich Mn3+${\rm Mn}^{3+}$ sites that render the surrounding ...
K. Nikolas Lausch   +3 more
wiley   +2 more sources

Engineering Na‐Rich P2‐Type Layered Oxides Through Li/Ti Dual Doping for Oxygen Redox Activation and Superior Structural Stability

open access: yesAdvanced Energy Materials, EarlyView.
P2‐type sodium layered oxides have potential for high‐voltage operation but suffer from structural instability and capacity fading. This work demonstrates that synergistic Li and Ti co‐doping enhances sodium inventory, suppresses detrimental phase transitions, and activates reversible lattice oxygen redox.
Rishika Jakhar   +16 more
wiley   +1 more source

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