Results 201 to 210 of about 117,023 (322)

Investigating the Ligand‐Binding Properties of N‐arylbenzimidazoles as Novel Elastase Inhibitors

ChemMedChem, EarlyView.
A series of novel N‐[(3,5‐dimethylphenyl)methyl]‐1H‐benzimidazole derivatives is designed, synthesized, and evaluated for inhibitory activity against elastase. Several compounds demonstrate an antielastase activity, including the N‐(2‐bromophenyl)‐2‐(6‐chloro‐1‐(3,5‐dimethylbenzyl)‐1H‐benzo[d]imidazol‐2‐ylthio)acetamide, showing the greatest potency ...
Giovanna Pitasi, Sonia Floris, Francesca Mancuso, Giulia Savoca, Rosaria Gitto, Antonella Fais, Laura De Luca   +6 more
wiley   +1 more source

Neopterin Concentration in Umbilical Cord Blood as a Reflection of Maternal Insulin Resistance-A Pilot Study. [PDF]

Biology (Basel)
Chęcińska-Kopeć A, Pruszynska-Oszmalek E, Checinska-Maciejewska Z, Rekas-Dudziak A, Wojciechowska M, Ślósarz P, Krauss H, Szymanowski K, Kolodziejski PA.   +8 more
europepmc   +1 more source

Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas

ChemMedChem, EarlyView.
Structure of the "hit‐compound" found and the proposed interaction with the active site of the TMPRSS2 protease, involving a reversible mechanism of action, are shown. The COVID‐19 pandemic highlighted the urgent need for effective antiviral treatments targeting SARS‐CoV‐2.
Marco Minneci, Barbara Farkaš, Adeyemi Rahman, Amy Kempf, Inga Nehlmeier, Stefan Pöhlmann, Isabel Rozas   +6 more
wiley   +1 more source

An integrated molecular-thermodynamic framework for analyzing nanobubbles in supersaturated liquids. [PDF]

RSC Adv
Ghamartale A, Shahini E, Jain A, Manica R, Berg P, Tang T.   +5 more
europepmc   +1 more source

Solvation Structure and Dynamics of the Thiocyanate Anion in mixed N,N‐Dimethylformamide‐Water Solvents: A Molecular Dynamics Approach

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The solvation structure and dynamics of the SCN− anion in mixed N, N‐Dimethylformamide (DMF)‐water liquid solvents is investigated using classical molecular dynamics simulations. A preferential solvation of SCN− by the water molecules is observed in the first hydration shell, followed by a second shell consisting by both DMF and water molecules.
Ioannis Skarmoutsos, Ilias G. Karvounis
wiley   +1 more source

PhotoChem Reference Chemical Database for the Development of New Alternative Photosafety Test Methods. [PDF]

Toxics
Lee GY, Hwang JH, Hong JH, Bae S, Lim KM.   +4 more
europepmc   +1 more source

Toward the Bioremediation of Nylon Waste Materials: Genome Mining Leads to the Identification of a Thermostable Laurolactamase From Thermopolyspora flexuosa

ChemSusChem, EarlyView.
To enhance nylon waste remediation, genome mining was used to identify a thermostable laurolactam hydrolase from Thermopolyspora flexuosa with activity against an important cyclic nylon derivative. Substrate scope analysis and structural modeling revealed key features controlling enzyme‐substrate compatibility, providing a promising foundation for ...
Maria E. Cleveland, Amir R. Bunyat‐zada, Esther R. Hoffman, Graeme W. Howe   +3 more
wiley   +1 more source

Translational framework for implementation evaluation and research: implementation strategies derived from normalization process theory. [PDF]

Implement Sci
May CR, Hillis A, Albers B, Desveaux L, Gilbert A, Girling M, Girling M, Kislov R, MacFarlane A, Mair FS, Potthoff S, Rapley T, Finch TL.   +12 more
europepmc   +1 more source

NPT再検討会議の成果と課題 NPT再検討会議の課題 : 日本の軍縮外交のために (被爆70年 : 核軍縮・不拡散特集)

, 2016
信将 秋山
openalex   +1 more source

Organic Electrolyte Composed of Strongly and Weakly Coordinating Molecules for Sodium‐Ion Battery. A Molecular Dynamics Simulation Study

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Molecular dynamics simulations reveal that the addition of weakly coordinating solvents disrupts stable Na+ solvation with various coordinating configurations, accelerating solvents exchange and promoting Na+ migration. The optimized electrolyte achieves the highest ionic conductivity as well as the fractional ionic conductivity of Na+ of 3.68 ± 0.36 ...
Hongjin Li, Junyu Huang, Yuechao Wu, Tao Wang, Siyuan Wu, Shu Li, Tianying Yan   +6 more
wiley   +1 more source