Results 81 to 90 of about 565 (91)
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LncRNA NR2F1-AS1 as a potential biomarker for prognosis in cancer patients: meta and bioinformatics analysis

Expert Review of Molecular Diagnostics, 2023
Previous studies have shown that the differential expression of lncRNA NR2F1-AS1 is closely related to the prognosis of cancer, but the conclusion is still controversial. Therefore, we conducted a meta-analysis and bioinformatics analysis to explore the correlation between LncRNA NR2F1-AS1 and cancer prognosis.From the beginning to January 25, 2023, we
Lu, Tang   +3 more
exaly   +3 more sources

LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p

Cytokine, 2023
The long noncoding RNAs' (lncRNAs) effect on cancer therapy resistance by targeting microRNA (miRNA) in the regulation of drug resistance genes has attracted more and more attention. This study attempted to explore the mechanism of "lncRNA NR2F1-AS1/miR-483-3p/IGF1″ axis in azacitidine resistance of THP-1 cells.THP-1 cells were treated with azacitidine
Shujun Li, Xielan Zhao
exaly   +3 more sources

High level of lncRNA NR2F1-AS1 predict the onset and progression of diabetic retinopathy in type 2 diabetes

Experimental Eye Research, 2022
This study aimed to investigate whether dysregulation of NR2F1-AS1 is associated with the T2D onset and DR progression. A total of 269 individuals diagnosed with T2D were recruited in this study, including 111 individuals with uncomplicated T2D and 158 individuals with nonproliferative diabetic retinopathy (NPDR).
Xinli, Ji, Jun, Sun, Zhanhong, Wang
exaly   +3 more sources

STAT3 activates the transcription of lncRNA NR2F1‐AS1 to promote the progression of melanoma via regulating the miR‐493‐5p/GOLM1 axis

Journal of Gene Medicine, 2021
AbstractBackgroundLong non‐coding RNAs (lncRNAs) are vital regulators during the biological processes of melanoma. The present study aimed to uncover biological functions of lncRNA termed NR2F1 antisense RNA 1 (NR2F1‐AS1) in melanoma and the potential mechanisms.MethodsRelative levels of NR2F1‐AS1 and miR‐493‐5p in a total of 137 paired primary ...
Xiong Wang
exaly   +3 more sources

lncRNA NR2F1-AS1 Regulates miR-17/SIK1 Axis to Suppress the Invasion and Migration of Cervical Squamous Cell Carcinoma Cells

Reproductive Sciences, 2020
lncRNA NR2F1-AS1 has been reported to be upregulated in hepatocellular carcinoma and plays oncogenic roles. Through the analysis of TCGA dataset, we observed the downregulation of NR2F1-AS1 in cervical squamous cell carcinoma (CSCC). This study was performed to analyze the functionality of NR2F1-AS1 in CSCC.
Hou Fang
exaly   +3 more sources

NR2F1-induced NR2F1-AS1 promotes esophageal squamous cell carcinoma progression via activating Hedgehog signaling pathway

Biochemical and Biophysical Research Communications, 2019
Emerging evidence has uncovered the extremely important roles of long noncoding RNAs (lncRNAs) in the progression of malignant tumors which includes numerous processes of gene regulation. LncRNA NR2F1-AS1 has been confirmed to have close correlation with the tumorigenesis of diverse cancers.
Yaowen Zhang   +2 more
exaly   +3 more sources

LncRNA NR2F1-AS1 is involved in osteogenic differentiation in fracture healing via miR-423-5p

open access: yesCytotechnology
To investigate the function and mechanism of action of LncRNA NR2F1-AS1 involved in osteogenic differentiation process. An in vitro model was constructed by osteogenic differentiation-induced stimulation (OS) on the hFOB1.19 cell line. Real-time fluorescence quantitative PCR (RT-qPCR) was performed to detect the expression of NR2F1-AS1, miR-423-5p and ...
Wenjun Ji
exaly   +4 more sources

LncRNA NR2F1-AS1 is involved in the progression of endometrial cancer by sponging miR-363 to target SOX4

Die Pharmazie, 2019
This study intended to investigate the role of lncRNA NR2F1-AS1 in endometrial cancer (EC). The expression level of NR2F1-AS1 in tumor tissues and EC cells was measured. After sh-NR2F1-AS1 transfection, the cell viability, apoptosis, migration and invasion of EC cells were analyzed. Luciferase reporter assay was conducted to investigate the target gene
Lei Wang, Lei Wang   +2 more
openaire   +2 more sources

NR2F1‐AS1 regulated miR‐423‐5p/SOX12 to promote proliferation and invasion of papillary thyroid carcinoma

Journal of Cellular Biochemistry, 2019
Abstract Papillary thyroid carcinoma (PTC) is an aggressive histological subtype of thyroid carcinoma (THCA), whose occurrence rate is high. The participation of long noncoding RNAs in the pathologies of cancers has attracted significant attention during the past decades.
Chuanjia Yang   +6 more
openaire   +2 more sources

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