Unlocking Lung Cancer Cell Dormancy: An Epigenetic Perspective. [PDF]
Fabrizio FP.
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Towards understanding cancer dormancy over strategic hitching up mechanisms to technologies. [PDF]
Yang S +8 more
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LncRNA UNC5C-AS1 inhibits angiogenesis and induces endothelial apoptosis via the miR-148a-3p/EMP1 axis in preeclampsia. [PDF]
Wang Y +6 more
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Integration of HiMoRNA and RNAChrom: Validation of the Functional Role of Long Non-coding RNAs in the Epigenetic Regulation of Human Genes Using RNA-Chromatin Interactome Data. [PDF]
Ilnitskiy IS +4 more
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Harnessing exosomal long non-coding RNAs as a new frontier for molecular diagnostics and therapeutics in diabetes mellitus. [PDF]
Midan HM +4 more
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Targeting Oncogenic lncRNA KRT7-AS to Induce Ferroptosis Suppresses Ovarian Cancer Progression. [PDF]
Zhu Y +9 more
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A review on the role of NR2F1-AS1 in the development of cancer
NR2F1-AS1 is a natural antisense transcript with prominent roles in the carcinogenesis. It acts as an oncogene in almost all types of cancers except for cervical and colorectal cancers. It can act as a molecular sponge for miR-17, miR-371a-3p, miR-363, miR-29a-3p, miR-493-5p, miR-190a, miR-140, miR-642a, miR-363, miR-493-5p, miR-483-3p, miR-485-5p, miR-
Soudeh Ghafouri-Fard +2 more
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NR2F1-AS1: A Functional Long Noncoding RNA in Tumorigenesis
Current Medicinal Chemistry, 2023Background: NR2F1-AS1 is a long non-coding RNA (lnc RNA) that is involved in different biological processes. It plays an integral role in the pathophysiology of human diseases, especially tumorigenesis and progression. Therefore, it may be a promising target for numerous tumor biotherapeutics.
Chengfu Yuan, Jiahui Hu, Jingjie Yang
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The emerging role of NR2F1-AS1 in the tumorigenesis and progression of human cancer
Pathology - Research and Practice, 2022Long noncoding RNAs (lncRNAs) are transcripts of more than 200 nucleotides that lack the ability to encode protein. Convincing studies have indicated that lncRNAs can act as oncogenes or tumor suppressors by regulating gene expression. The novel lncRNA NR2F1-AS1 was recently found to be abnormally expressed in various malignancies, including ...
Dong, Luo +8 more
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A recent study reported the oncogenic function of lncRNA NR2F1-AS1 in liver cancer. Interestingly, by analyzing TCGA data set, downregulation of NR2F1-AS1 in colorectal cancer (CRC) was observed. This observation triggered interest to analyze the functions of NR2F1-AS1 in CRC.
Jianguang Wang
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