Results 71 to 80 of about 410,492 (225)

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Sleep Related Epilepsy and Pharmacotherapy: An Insight

open access: yesFrontiers in Pharmacology, 2018
In the last several decades, sleep-related epilepsy has drawn considerable attention among epileptologists and neuroscientists in the interest of new paradigms of the disease etiology, pathogenesis and management.
Jaya Kumar   +5 more
doaj   +1 more source

Characterizing Sleep Structure Using the Hypnogram

open access: yes, 2008
Objectives: Research on the effects of sleep-disordered breathing (SDB) on sleep structure has traditionally been based on composite sleep-stage summaries.
Caffo, Brian   +3 more
core   +1 more source

Decoding Sleep Architecture from Ambulatory Basal Ganglia Signals in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Sleep architecture and circadian rhythms are frequently disrupted in Parkinson's disease (PD). BrainSense‐enabled neurostimulators combined with wearable technology enable chronic assessment of nocturnal brain activity, with potential for future diagnostics and personalized treatments. Objectives To neurophysiologically characterize
Alberto Averna   +15 more
wiley   +1 more source

Artificial intelligence in out‐of‐hospital sleep monitoring: Bridging polysomnography and wearable signals

open access: yesSleep Research, EarlyView.
Abstract Polysomnography (PSG), the reference standard for sleep assessment, has limited scalability for large‐scale screening, driving the development of wearable and unobtrusive monitors. However, the physiological signals these devices capture are physiologically correlated with PSG channels but are not completely equivalent.
Jing Yan   +5 more
wiley   +1 more source

Sleep and cognition [PDF]

open access: yes, 2014
Sleep is an ancestral and primitive behaviour, an important part of life thought to be essential for restoration of body and mind. As adults, we spend approximately a third of our lives asleep and as we progress through life there are certain shifts in ...
Wright, Hayley   +11 more
core   +1 more source

Asymmetric sleep spindles after thalamic stroke

open access: yes
Epileptic Disorders, EarlyView.
Côme‐Alexandre Meyruey   +1 more
wiley   +1 more source

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Dysregulation of Sleep Behavioral States in Narcolepsy

open access: yes, 2017
Study Objectives Patients with narcolepsy suffer from poor maintenance of wakefulness and fragmented night sleep, but the underlying mechanism of sleep boundary dysregulation remains little understood.
Rositsa Poryazova   +11 more
core   +1 more source

Destabilization of light NREM sleep by thalamic PLC beta 4 deletion impairs sleep-dependent memory consolidation [PDF]

open access: yes, 2020
Sleep abnormality often accompanies the impairment of cognitive function. Both rapid eye movement (REM) and non-REM (NREM) sleep have associated with improved memory performance.
Hong, Joohyeon   +6 more
core   +1 more source

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