Results 81 to 90 of about 844,158 (279)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Experimental Evaluation of LoRaWAN in NS-3 [PDF]
8 pages, 11 ...
Khan, Furqan Hameed, Portmann, Marius
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The new generation mobile network 5G has become the main technology foundation in the architecture of the Internet of Things (IoT). In particular, millimeter wave communication technology in 5G is the core technology of the new generation network ...
Nguyen Quoc Dung
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Analysis of source code metrics from ns-2 and ns-3 network simulators [PDF]
Ns-2 and its successor ns-3 are discrete-event simulators which are closely related to each other as they share common background, concepts and similar aims. Ns-3 is still under development, but it offers some interesting characteristics for developers
Amaya Rodríguez, Claudio Antonio +4 more
core
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Introducing a Distance Vector Routing Protocol for ns-3 Simulator
In network research, network simulators have been shown to be useful for testing and changing network protocols by means of a controlled manner. As an Internet systems simulator, ns-3 simulator provides an ideal simulation environment for network ...
Janaka Wijekoon +3 more
doaj +1 more source
Wireless Channel 802.11 in NS-3
Network Simulators (NS) is typically used to study services and applications in complex scenarios due to the infeasibility of deploying real testbeds. This is the case of Mobile Ad hoc Networks (MANETs) which can be extensively used in emergency situations or to gather information without infraestructure. An important factor to get realiable results in
Lesly Maygua-Marcillo +2 more
openaire +2 more sources

