Results 111 to 120 of about 18,026 (178)

Cumulative EA Incidence with Combinations of Abnormalities (17p LOH, DNA Content Abnormality, 9p LOH) in NSAID Nonusers and NSAID Users

open access: yes, 2013
Cancer incidence rates are shown for participants with no selected abnormalities (17p LOH, DNA content abnormalities [aneuploidy and/or tetraploidy], or 9p LOH) at baseline (red), any one abnormality (green), any combination of two abnormalities (blue ...
Carissa A Sanchez (379240)   +9 more
core   +1 more source

Transcriptomic Profiling in Skeletal Muscle Identifies Associations With Knee Osteoarthritis: the Study of Muscle, Mobility and Aging (SOMMA)

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The association between skeletal muscle gene expression and knee osteoarthritis (OA) was examined among older adult participants of the Study of Muscle, Mobility and Aging (SOMMA). Methods Inclusion criteria included knee radiographs and bulk RNA sequencing (RNAseq) in vastus lateralis muscle, resulting in 523 participants (56% female ...
Daniel S. Evans   +7 more
wiley   +1 more source

Early diagnosis of axial spondyloarthritis is associated with less long‐term spinal structural damage: a longitudinal analysis of the Swiss Clinical Quality Management in rheumatic diseases registry

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The Assessment of SpondyloArthritis international Society recently defined early axial spondyloarthritis (axSpA) as a duration ≤2 years of axial symptoms. Previous studies have shown no significant difference in short‐term outcomes between early and established axSpA patients treated with biologic/targeted synthetic disease‐modifying anti ...
Annik Steimer   +18 more
wiley   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck   +2 more
wiley   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus   +6 more
wiley   +1 more source

Generation of Risk Score for Serious Non-Steroidal Anti-Inflammatory Drug (NSAID) Induced Cardiovascular Events (NAÏVE) Among Active-Duty Service Members and Veterans

open access: yesJournal of Pain Research
Timothy J Atkinson,1 Justin Petway,2 Whitney L Forbes,3 Hannah Thorfinnson,4 Ryan C Costantino,3,5 Laura E Gressler6 1Pain Management, Opioid Safety, PDMP (PMOP), National Program Office, Department of Veterans Affairs, Washington, DC, USA; 2Pharmacy ...
Atkinson TJ   +5 more
doaj  

Treatment and prophylaxis of NSAID-induced gastropathies in a therapeutist’s practice

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2009
The aim of review – to present up-to-date data on application of proton pump inhibitors (PPI) e.g. esomeprazole for treatment and prophylaxes of gastropathies, induced by intake of nonsteroid anti-inflammatory drugs (NSAIDs).Original positions. PPI serve
T. L. Lapina
doaj  

When allergy strikes the heart: Kounis syndrome and cardiac arrest

open access: yesEuropean Journal of Case Reports in Internal Medicine
Introduction: Kounis syndrome is an acute coronary syndrome precipitated by allergic or hypersensitivity reactions and mediated by the release of inflammatory substances that affect the coronary circulation.
Marta Chiara Sircana   +3 more
doaj   +1 more source

H. pylori eradication therapy for patients receiving nonsteroid antiinflammatory drugs

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To demonstrate value of H. pylori eradication therapy in patients for prophylaxis and treatment of nonsteroid antiinflammatory drugs (NSAID)- induced gastropathies.Key points. NSAID and H.
V. T. Ivashkin, T. L. Lapina
doaj  

Effectiveness of transdermal NSAID administration in analgesia for rib fracture patients: a comparative study with intravenous NSAID administration

open access: yes, 2018
Background: Simple rib fractures are the most common injuries sustained following blunt trauma chest, accounting for more than half of thoracic injuries from nonpenetrating trauma.
Vikas Sankar Kottareddygari   +4 more
core   +1 more source

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