Objectives: To determine which class of non-opioid analgesics – paracetamol (acetaminophen), NSAIDs or COX-2 inhibitors – is the most effective at reducing morphine consumption and associated adverse effects when used as part of multimodal analgesia ...
Catriona McDaid +5 more
doaj +1 more source
A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans +5 more
core
Systematic study of constitutive cyclo-oxygenase-2 expression: role of NFκB and NFAT transcriptional pathways [PDF]
Cyclooxygenase-2 (COX-2) is an inducible enzyme that drives inflammation and is the therapeutic target for widely used nonsteroidal antiinflammatory drugs (NSAIDs).
Ahmetaj-Shala, B +11 more
core +1 more source
Purpose: To compare the effect of topical 1% prednisolone acetate and 0.09% bromfenac versus topical 1% prednisolone acetate alone on macular thickness following Nd: YAG laser capsulotomy.
Monica Deshwal +3 more
doaj +1 more source
A Review Of Drug Allergies: Diagnosis and Management
Drug allergy, in clinical practice, includes a wide spectrum of immunologically-mediated hypersensitivity reactions, also called drug hypersensitivity reactions (DHRs).
Arvind Bamanikar
doaj
Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer : a case-control study in a population with relatively low folate intake [PDF]
Peer reviewedPublisher ...
Andreassi +26 more
core +1 more source
Safety, Tolerability, and Effect on Opioid Use of Meloxicam IV Following Orthopedic Surgery
Kipling P Sharpe, 1 Richard Berkowitz, 2 William A Tyndall, 3 David Boyer, 4 Stewart W McCallum, 5 Randall J Mack, 5 Wei Du 6 1OrthoArizona, Gilbert, AZ, USA; 2Phoenix Clinical Research, Tamarac, FL, USA; 3University Orthopedics Center, Altoona, PA ...
Sharpe KP +6 more
doaj
Seizure Disorders in Goats and Sheep. [PDF]
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core +1 more source
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core +2 more sources
Julie Pradal GlaxoSmithKline Consumer Healthcare S.A, Nyon 1260, SwitzerlandCorrespondence: Julie PradalGSK Consumer Healthcare S.A., Route De l’Etraz 2, Nyon 1260, SwitzerlandTel +41 22 567 26 72Email julie.x.pradal@gsk.comPurpose: The therapeutic
Pradal J
doaj

