Results 81 to 90 of about 18,026 (178)

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Highlighting the Effect of Pro-inflammatory Mediators in the Pathogenesis of Periodontal Diseases and Alzheimer’s Disease

Journal of Pharmacy and Bioallied Sciences
Alzheimer’s disease (AD) is a neurological condition that is much more common as people get older. It may start out early or late. Increased levels of pro-inflammatory cytokines and microglial activation, both of which contribute to the central nervous ...
Babiker Rasha, Mohammed Riham, Chaitanya Nallan CSK, Rahman Muhammed M, Gismalla Bakri   +4 more
doaj   +1 more source

Periodontal Diseases and Host Modulation Therapies

Journal of Pharmacy and Bioallied Sciences
In periodontal diseases, bacteria and microbes serve as the primary pathogens that initiate the condition, while the host refers to the body that hosts these microorganisms.
Abdulaziz Alsakr
doaj   +1 more source

Strong topical steroid, NSAID, and carbonic anhydrase inhibitor cocktail for treatment of cystoid macular edema

, 2015
Masumi G Asahi, Gabriela L Bobarnac Dogaru, Spencer M Onishi, Ron P GallemoreRetina Macula Institute, Torrance, CA, USA Purpose: To report the combination cocktail of strong steroid, non-steroidal anti-inflammatory drug (NSAID), and carbonic anhydrase ...
Asahi MG, Onishi SM, Bobarnac Dogaru GL, Gallemore RP   +3 more
core  

High Rate of Return to Sport in Competitive Athletes Undergoing Periacetabular Osteotomy With Concomitant Hip Arthroscopy

Arthroscopy, EarlyView.
Purpose To report the return‐to‐sport rate of competitive athletes with hip dysplasia, in relation to their preoperative level of competition, who underwent hip arthroscopy with concomitant periacetabular osteotomy (HA + PAO). Methods Patients participating in competitive sports who underwent HA + PAO for the correction of hip dysplasia between January
Alfred Mansour, Nicole Lemaster, Jacob Jelmini, Philip Sheedy, Anota Adekunle, Alexis Aboulafia   +5 more
wiley   +1 more source

Caution with NSAIDs [PDF]

British Dental Journal, 2020
Crighton, A., McCann, C., Todd, E., Brown, A.   +3 more
openaire   +2 more sources

Observational survey of NSAID-related upper gastro-intestinal adverse events in Belgium.

, 2002
To evaluate the impact of NSAID use on current routine upper GI endoscopy (UGIE) and to compare the lesions found in NSAID users and non-users. Participating gastroenterologists consecutively documented outpatients with and without suspicion of bleeding,
Belaiche, J, De Vos, M, Huybrechts, M, Fiasse, René, Louis, E, Belgian Study Group of NSAID-GI Complications, Burette, A, Deltenre, M, Deprez, C. P.   +8 more
core  

Statin and NSAID usage.

, 2014
Statin and NSAID usage.
Nola Olsen (610368), Amy Walsh (610367), Bruce W. S. Robinson (341821), Anna K. Nowak (370618), Arthur W. Musk (174646), Cleo Robinson (610365), Samantha Woo (610366), Helman Alfonso (246869), Richard A. Lake (370627)   +8 more
core   +1 more source

Preoperative Risk Factors for Opioid Use Predict Self‐Reported Health and Function Up to 6 Months After Anterior Cruciate Ligament Reconstruction

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To identify risk factors that predict the need for rescue opioid use and patient‐reported outcomes following an opioid‐limiting postoperative analgesia protocol after anterior cruciate ligament reconstruction. Methods This prospective cohort study recruited 44 patients undergoing primary arthroscopic‐assisted anterior cruciate ligament ...
Eric V. Neufeld, William DeGouveia, Camille Pinpin, Matthew Zinner, Michael J. Sayegh, Michael J. Meade, Steven E. Rokito   +6 more
wiley   +1 more source

Treatment and chemoprevention of NSAID-associated gastrointestinal complications

, 2008
Edward J Frech1,2, Mae F Go1,21GI Section, George E Wahlen Department of Veterans Affairs Medical Center; 2Division of Gastroenterology, University of Utah School of Medicine, Salt Lake City, Utah, USAAbstract: The use of non-steroidal anti-inflammatory ...
Mae F Go, Edward J Frech
core