Results 101 to 110 of about 104,757 (302)
Clinical Pharmacology in Drug Development, EarlyView.Abstract Long‐acting (LA) cabotegravir 200‐mg/mL (CAB200) injections are approved for HIV‐1 prevention and as a complete LA HIV‐1 treatment regimen with rilpivirine. A high‐concentration suspension formulation, cabotegravir 400 mg/mL (CAB400‐D), was developed to enable less frequent dosing and self‐administration. This phase 1, double‐blind, randomized
Kelong Han +16 more
wiley +1 more source
JOR SPINE, Volume 5, Issue 4, December 2022., 2022 Abstract Intervertebral disc degeneration is a common cause of low back pain, the leading cause of disability worldwide. Appropriate preclinical models for intervertebral disc research are essential to achieving a better understanding of underlying pathophysiology and for the development, evaluation, and translation of more effective treatments.
Shirley N. Tang +13 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Adverse drug reactions (ADRs) are a common cause of morbidity and mortality in hospitalized patients. Identification of ADRs in clinical practice, surveillance and research is essential to prevent further harm. The aim of this study was to assess the likelihood of drugs contributing to clinically important inpatient adverse events, in order to provide ...
Anna Maria Wermund +5 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin +7 more
wiley +1 more source
Prophylaxis of NSAID Associated Gastroduodenal damage: A Critical Review of Risk Factors [PDF]
, 1993 DJ Leddin
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Clinical Pharmacology &Therapeutics, EarlyView.Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman +14 more
wiley +1 more source
Вісник проблем біології і медицини, 2019 The article investigated changes in the level of CTX I marker under the influence of non-steroidal antiinflammatory drugs and paracetamol under experimental equivalents of hypothyroidism and osteoarthritis.
Nosivets D. S.
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NSAIDS in the postoperative period. Don't dismiss gastric erosion. [PDF]
, 1993 G C Fenn
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