Results 111 to 120 of about 125,582 (281)

Machine Learning to Predict Remission Between 6 and 24 Months in Rheumatoid Arthritis: Insights From JAK, an International Registry Collaboration

Arthritis &Rheumatology, EarlyView.
Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis, Denis Mongin, Denis Choquette, Louis Coupal, Catalin Codreanu, Florenzo Iannone, Roberto Caporali, Tore K. Kvien, Sella Provan, Ruth Fritsch‐Stork, Dan Nordström, Nina Trokovic, Karel Pavelka, Jakub Závada, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Irini Flouri, Céline Lamacchia, Michele Iudici, Delphine Courvoisier, Kim Lauper, Axel Finckh   +22 more
wiley   +1 more source

Intra-Individual Variability in Self-Reported Use of Non-Steroidal Anti-Inflammatory and Analgesic Medicines Depending on Mode of Data Collection - Observations from the Population Study of Women in Gothenburg, Sweden

International Journal of General Medicine, 2021
Helle Håkonsen,1 Dominique Hange,1,2 Tove Hedenrud1 1School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, SE 405 30, Sweden; 2Region Västra Götaland, Education, Research and Development Primary ...
Håkonsen H, Hange D, Hedenrud T
doaj  

NSAIDs:Cardiovascular risks

, 2017
The connection between the cardiovascular system and prostaglandins with the role they play and how NSAIDs may eventually influence cardiovascular diseases is discussed. It helps to understand how the effects and side effects that these everday drugs may
Dukku, Aisha Bappah
core  

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Formulation and in-vitro evaluation of oxaprozin transdermal patches for sustained anti-inflammatory therapy

Journal of Applied Pharmaceutical Research
Background: Inflammation is characterized by pain, altered membrane permeability, increased vascular activity, and protein denaturation. Oxaprozin, a BCS Class II NSAID, is often used to manage inflammation and pain but is limited by poor solubility and ...
Mansi Gupta, Priya Tiwari
doaj   +1 more source

Penetration and efficacy of transdermal NSAIDs in a model of acute joint inflammation

, 2018
David Charles Baranowski,1 Beth Buchanan,1 Heather C Dwyer,1 Joseph P Gabriele,1 Stephanie Kelly,2 Joseph A Araujo3 1Department of Research and Development, Delivra Corp., Charlottetown, PE, Canada; 2Vivocore Inc, Toronto, ON, Canada; 3InterVivo ...
Buchanan B, Kelly S, Baranowski DC, Gabriele JP, Dwyer HC, Araujo JA   +5 more
core  

High‐Resolution Deep Learning Dixon Magnetic Resonance Imaging of the Sacroiliac Joints Is Noninferior to Standard Magnetic Resonance Imaging in Patients With Suspected Axial Spondyloarthritis

Arthritis &Rheumatology, EarlyView.
Objective To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high‐resolution deep learning–reconstructed Dixon sequence (DL‐Dixon) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical,
Dominik Deppe, Mariam Koka, Fabian Proft, Sevtap Tugce Ulas, Kay‐Geert Hermann, Denis Poddubnyy, Mikhail Protopopov, Henriette Baum, Hildrun Haibel, Mehrgan Shahryari, Valeria Rios Rodriguez, Jens Vogel‐Claussen, Torsten Diekhoff   +12 more
wiley   +1 more source

The Role of NSAIDs in Chronic Inflammatory Disorders: Efficacy, Risks, and New Developments

This thesis has taken a close look at nonsteroidal anti-inflammatory drugs (NSAIDs) as a treatment of chronic inflammatory disorders, using evidence from meta-analyses, experimental work, and clinical studies.
Sagdatova, Ulzhan
core  

Individual NSAIDs and Upper Gastrointestinal Complications

, 2012
Background: The risk of upper gastrointestinal (GI) complications associated with the use of NSAIDs is a serious public health concern. The risk varies between individual NSAIDs; however, there is little information on the risk associated with some ...
Susana Perez-Gutthann, Fourrier-Reglat, A, Riera-Guardia, N, Perez-Gutthann, S, Sturkenboom, MCJM, Nuria Riera-Guardia, Brian Calingaert, Jordi Castellsague, Miriam Sturkenboom, Calingaert, B, null null, Federica Nicotra, Varas-Lorenzo, C, Nicotra, F (Federica), Cristina Varas-Lorenzo, Annie Fourrier-Reglat, Castellsague, J   +16 more
core   +1 more source