Results 121 to 130 of about 125,582 (281)

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco   +8 more
wiley   +1 more source

NSAIDs: take with food or after fasting?

open access: yes, 2011
Objective Published and regulatory advice is to take NSAIDs with fluids and/or food irrespective whether NSAIDs are taken over the counter or long-term.
Ingvar Bjarnason, Kim D Rainsford
core   +1 more source

Proximal Fibular Osteotomy: A Refined Surgical Technique for Medial Compartment Knee Osteoarthritis

open access: yesArthroscopy Techniques, EarlyView.
Abstract Proximal fibular osteotomy is a minimally invasive and cost‐effective option for medial compartment knee osteoarthritis. This refined technique, performed under spinal anesthesia using Henry's posterolateral approach, involves a small incision approximately 10 cm distal to the fibular head, careful dissection through the peroneus longus plane,
Mohammad Ayati Firoozabadi   +5 more
wiley   +1 more source

NSAIDs, hypertensjon og kardiovaskulære hendelser

open access: yes, 2011
Objective A literature review of the effects of non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure and cardiovascular risk. Background NSAIDs are used for relieving pain in many conditions.
Lee, Kang Ching
core  

An investigation of the neuropharmacological and behavioural effects of fenamate and other NSAIDs. [PDF]

open access: yes, 2001
Recent evidence has indicated that NSAIDs might have direct effects on CNS tissue in addition to their classical inhibitory action on COX enzymes. This thesis addresses this hypothesis using electrophysiological and behavioural techniques. The effects of
Foxon, Graham Ronald
core  

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin   +3 more
wiley   +1 more source

Prescribing competence: The pros and cons of different methods for assessment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman   +3 more
wiley   +1 more source

A study to evaluate anti-oxidant and anti-inflammatory activity of curcumin longa and fenugreek in osteoarthritis – A randomized, triple blind, placebo controlled clinical trial [PDF]

open access: yesAl Ameen Journal of Medical Sciences
Background: Osteoarthritis (OA), is a leading causes of disability. Herbal medications are often used as an alternative to allopathic drugs to manage symptoms of osteoarthritis.
Sachin Panwar   +4 more
doaj  

Evaluating and leveraging large language models in clinical pharmacology and therapeutics assessment: From exam takers to exam shapers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard   +11 more
wiley   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez   +2 more
wiley   +1 more source

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