Results 131 to 140 of about 143,857 (295)

Evaluating a virtual paediatric adverse drug reaction clinic

British Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck, Blanca Del Pozzo‐Magana, Michael Rieder   +2 more
wiley   +1 more source

ADR Monitoring of NSAIDs among the in-Patients of the Orthopaedic Ward in a Tertiary Care Centre: A Prospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research, 2012
Background: The non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used of all the drugs. Despite their wide clinical use, their gastro-intestinal toxicity is a major limitation. A number of studies describe NASIDs as the leading
SIVASANKARI VENKATACHALAM, RAMACHANDRA BHAT   +1 more
doaj  

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

A study to evaluate anti-oxidant and anti-inflammatory activity of curcumin longa and fenugreek in osteoarthritis – A randomized, triple blind, placebo controlled clinical trial [PDF]

Al Ameen Journal of Medical Sciences
Background: Osteoarthritis (OA), is a leading causes of disability. Herbal medications are often used as an alternative to allopathic drugs to manage symptoms of osteoarthritis.
Sachin Panwar, Swati Saxena, Akhlaque Ahmad, Dilip Kumar Singh, Sarvesh Singh   +4 more
doaj  

Nonrheumatologic Uses of NSAIDS

, 1984
Nonsteroidal anti inflammatory drugs (NSAIDs) have several salient indications outside of their role in rheumatology. Two major uses are treatment of dysmenorrhea and patent ductus arteriosus.
Ronald P. Evens
core   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing

British Journal of Clinical Pharmacology, EarlyView.
The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët, Steven R. Kraaijeveld, Erik M. Donker, Milan C. Richir, Caroline T. A. Moermond, Amy Booth, SanYuMay Tun, Thijs H. Oude Munnink, Patricia M. L. A. van den Bemt, Lorena Dima, Ben J. A. Janssen, Mathilde Jalving, Tomás Mauro van Emden, Fabrizio de Ponti, Robert Likic, João Costa, Marc Labriffe, Charlotte L. Bekker, Carlotta Lunghi, Elisabetta Poluzzi, Michiel A. van Agtmael, Yolande Voskes, Jelle Tichelaar   +22 more
wiley   +1 more source

Practice‐level variation in potentially inappropriate prescribing in middle‐aged adults: A repeated cross‐sectional study in South London general practice

British Journal of Clinical Pharmacology, EarlyView.
Aim To quantify between‐practice variation in potentially inappropriate prescribing (PIP) among middle‐aged adults (45–64 years) in UK general practice, and to identify patient‐ and practice‐level characteristics associated with PIP. Methods Repeated cross‐sectional study using linked data from the Lambeth DataNet and Quality Outcomes Framework across ...
Ryan Jayesinghe, Amandeep Khatter, Stevo Durbaba, Mark Ashworth, Benjamin Jacob, Frank Moriarty, Patrick Redmond   +6 more
wiley   +1 more source

Comparative treatment effects of direct oral anticoagulants versus warfarin for nonvalvular atrial fibrillation in clinical practice vary over time due to channelling

British Journal of Clinical Pharmacology, EarlyView.
Aim Temporal shifts in patient characteristics can influence comparative treatment effects within a certain indication. We investigated patient characteristics and comparative effectiveness and safety for direct oral anticoagulants (DOACs) and warfarin over the time period where DOACs replaced warfarin as preferred stroke prophylaxis in patients with ...
Raoul B. L. J. van den Hemel, Aernoud T. L. Fiolet, Magdalena A. Gamba, Patrick C. Souverein, Olaf H. Klungel, Lourens T. Bloem, Sophie H. Bots   +6 more
wiley   +1 more source

It is wise to prescribe NSAIDs with modern gastroprotective agents?

, 1987
The administration of non-steroidal anti-inflammatory drugs (NSAIDs) leads to mucosal lesions in the upper gastrointestinal tract. Furthermore, NSAIDs increase the risk of ulcer bleeding and perforation, but the overall risk of fatal complications is ...
Blum AL, Emde C, Cucala M, Koelz HR, Gonvers JJ, Bauerfeind P, J. J. Gonvers, M. Cucala, H. R. Koelz, P. Bauerfeind, C. Emde, A. L. Blum   +11 more
core   +1 more source