Results 251 to 260 of about 355,709 (346)

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation

open access: yesMed Research, EarlyView.
Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin   +4 more
wiley   +1 more source

Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC

open access: yesCancer immunology research, 2017
P. Tumeh   +33 more
semanticscholar   +1 more source

ALCAM-CD6 axis suppression: a key determinant of immune-mediated metastasis recurrence in stage III non-small cell lung cancer. [PDF]

open access: yesJ Immunother Cancer
Wen S   +13 more
europepmc   +1 more source

A case-controlled study comparing sleeve lobectomy and standard lobectomy of NSCLC

open access: bronze, 2003
Masahiko Harada   +4 more
openalex   +2 more sources

Osimertinib and other third-generation EGFR TKI in EGFR-mutant NSCLC patients

open access: yesAnnals of Oncology, 2018
J. Remon   +3 more
semanticscholar   +1 more source

PD-L1 regulates c-MET phosphorylation and contributes to MET-dependent resistance to osimertinib in EGFR-mutant NSCLC. [PDF]

open access: yesJ Biomed Sci
Hsu CC   +11 more
europepmc   +1 more source

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