Results 191 to 200 of about 16,958 (303)

Unconventional-Phase 1T'-Transition Metal Dichalcogenide Monolayers Grown on Amorphous Templates for Highly Efficient Hydrogen Evolution. [PDF]

J Am Chem Soc
Li Z, Yang H, Sun M, Zhang A, Ge Y, Long X, Huang B, Zhai L, Zhai W, Li L, Wang L, Wang C, Xu Y, Cai Y, Liu P, Chen B, Gu L, Qiao P, Zhang Q, Ding F, Zhang H.   +20 more
europepmc   +1 more source

Global Regulation of Time-Delay Cascade Systems via Partial State Feedback**This work was supported in part by Key Project of NSFC under Grant 61533009, 61273141 and 2014CB046406, 111 Project (B08015), Research Projects (KQC201105300002A), (JCY201303291521257) and (JCYJ20150403161923519).

IFAC-PapersOnLine, 2016
Xu Zhang, Wei Lin, Yan Lin
openaire   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Asymmetric Bi and S Single Atoms Over Porous Single-Crystal TiO₂ for Efficient CO₂ Photoreduction to Acetic Acid. [PDF]

Adv Mater
Jia G, Wang Y, Sun M, Zhang Y, Xie Z, Cui X, Huang B, Yu JC, Guo Z.   +8 more
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Host-Guest Interactions Enhance Charge Transport across Single Cyclodextrin/Azobenzene Complex Junction. [PDF]

J Am Chem Soc
Han S, Zhao J, Naskar S, Wu D, Herrmann C, Xia J, Li H.   +6 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

A monocyte-centered framework for predicting immunochemotherapy efficacy in lung squamous cell carcinoma patients. [PDF]

EMBO Mol Med
Zhao J, Wang Z, Xiao M, Zhang Y, Liu B, Chen S, Tian Y, Lv D, Wang P, Song H, Wu Y, Liu J, Wang K.   +12 more
europepmc   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

A Room-Temperature Rh-Catalyzed Kinetic Resolution Pathway for Expedient Access to <i>P</i>‑Stereogenic Cyclic Phosphinates. [PDF]

JACS Au
Gu X, Ke XY, Choy PY, Ni SF, Wang J, Kwong FY.   +5 more
europepmc   +1 more source