Results 171 to 180 of about 34,742 (282)

Global Regulation of Time-Delay Cascade Systems via Partial State Feedback**This work was supported in part by Key Project of NSFC under Grant 61533009, 61273141 and 2014CB046406, 111 Project (B08015), Research Projects (KQC201105300002A), (JCY201303291521257) and (JCYJ20150403161923519).

IFAC-PapersOnLine, 2016
Xu Zhang, Wei Lin, Yan Lin
openaire   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Substorm expansion embedded in a global cycle of field-aligned currents and auroral electrojets. [PDF]

Nat Commun
Wang T, Dai L, Escoubet CP, Gonzalez W, Ren Y, Zhu M, Wang S, Wang C, Wang X, Wang K, Liu J.   +10 more
europepmc   +1 more source

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Proton-activated chloride channel PACC1 as acid sensor in epidermal desquamation. [PDF]

Proc Natl Acad Sci U S A
Xia K, Liu X, Wu J, Hu J, Cheng X, Mi T, Gao B, Mo X, Lu X, Cao F, Xie C, Cao J, Pernodet N, He G, Zhou H, Yao J.   +15 more
europepmc   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

A Room-Temperature Rh-Catalyzed Kinetic Resolution Pathway for Expedient Access to <i>P</i>‑Stereogenic Cyclic Phosphinates. [PDF]

JACS Au
Gu X, Ke XY, Choy PY, Ni SF, Wang J, Kwong FY.   +5 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

Construction of Heteroleptic Copper Complexes in Perylene Diimide-Based COFs for Heterogeneous Metallaphotoredox Catalysis. [PDF]

J Am Chem Soc
Wu X, Guo J, Sun MY, Du T, Hao D, Liu D, Wang D, Wen S, Yin J, Li D, He J.   +10 more
europepmc   +1 more source