Results 271 to 280 of about 17,202,806 (309)
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BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones

NeuroReport, 1993
The effects of neurotrophins on intracellular Ca2+ levels in rat hippocampal neurones were studied in vitro using fura-2 fluorescence microscopy. BDNF and NT-3, but not NGF, rapidly increased cytoplasmic Ca2+ concentrations in these neurones ten-fold to reach 1 microM.
B, Berninger   +4 more
openaire   +2 more sources

The role of NT-3 signaling in Merkel cell development

2004
Merkel cells originate from the neural crest. They are located in hairy and glabrous skin and have neuroendocrine characteristics. Together with A beta afferents, Merkel cells form a slowly adapting mechanoreceptor, the Merkel nerve ending, which transduces steady skin indentation.
Maya, Sieber-Blum   +2 more
openaire   +2 more sources

Synergistic effects of BDNF and NT-3 on postnatal spiral ganglion neurons

The Journal of Comparative Neurology, 1997
Neurotrophins have profound effects on the development and maintenance of neurons that compose the VIIIth cranial nerve. In the auditory division of the nerve, brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) have been localized to the sensory epithelium, and their respective high-affinity tyrosine kinase receptors (TrkB and TrkC) are
K, Mou   +3 more
openaire   +2 more sources

NT-3. Takeda/Regeneron/Amgen.

IDrugs : the investigational drugs journal, 2005
Regeneron, in collaboration with Amgen, is developing neurotrophin-3 (NT-3), a neuronal growth factor, for the potential treatment of neuropathies, as well as Parkinson's disease (PD). The product was inlicensed from Takeda Chemical Industries [179174].
openaire   +1 more source

NT-3: an Additional Neurotrophin Expressed in the Adult Rat Pituitary

Endocrine Research, 1999
Neurotrophins mediate a variety of essential biological functions in the nervous system. Evidence has emerged that this class of proteins is also implicated outside the nervous system, in the pituitary. The study described here aims to understand the expression of neurotrophins in the pituitary.
openaire   +2 more sources

Evaluation of Cisplatin Neuroprotection by NT‐3

Annals of Neurology, 1996
CAVALETTI, GUIDO ANGELO   +1 more
openaire   +2 more sources

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

Neuron, 1990
P. Maisonpierre   +7 more
semanticscholar   +1 more source

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