Results 71 to 80 of about 238,371 (341)

Inverse association of N-terminal pro-B-type natriuretic peptide with metabolic syndrome in patients with congestive heart failure. [PDF]

PLoS ONE, 2013
BACKGROUND: Metabolic syndrome has been shown to be associated with lower levels of plasma N-terminal pro-B-type natriuretic peptide (Nt-proBNP) in the general population.
Huai-Ren Chang, Jen-Che Hsieh, Bang-Gee Hsu, Ling-Yi Wang, Michael Yu-Chih Chen, Ji-Hung Wang   +5 more
doaj   +1 more source

B-type natriuretic peptide versus amino terminal pro-B type natriuretic peptide: selecting the optimal heart failure marker in patients with impaired kidney function [PDF]

, 2013
Background: The effect of impaired kidney function on B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) is vague. This study was performed to examine the effect of kidney dysfunction on the afore-mentioned markers and determine ...
Azam, Iqbal, Ghani, Farooq, Jafri, Lena, Kashif, Waqar, Shahzad, Hira, Siddiqui, Imran, Tai, Javed   +6 more
core   +2 more sources

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

Body mass index modifies the major adverse cardiovascular and cerebral events risk of NT-proBNP in patients with acute coronary syndrome

Diabetology & Metabolic Syndrome
Background Little is known about the relationship between body mass index (BMI) and the prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with acute coronary syndrome (ACS).
Xiaoquan He, Xiaojing Fang, Jiali Wang, Shumei Zhao, Xiaosong Ding, Hui Chen   +5 more
doaj   +1 more source

NT-proBNP for risk prediction of cardiovascular events and all-cause mortality: The getABI-study

International Journal of Cardiology: Heart & Vasculature, 2020
Background Beside their role in the diagnosis of heart failure in symptomatic patients with dyspnea, natriuretic peptides have been suggested to improve risk prediction of cardiac events and mortality in asymptomatic cohorts.
Henrik Rudolf, A. Mügge, H. Trampisch, H. Scharnagl, Winfried März, Winfried März, Winfried März, K. Kara   +7 more
semanticscholar   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Differences in NT‐proBNP Response and Prognosis in Men and Women With Heart Failure With Reduced Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) is a prognostic biomarker in heart failure (HF) with reduced ejection fraction. However, it is unclear whether there is a sex difference in NT‐proBNP response and whether the therapeutic ...
Melissa A. Daubert, Eric Yow, Huiman X. Barnhart, Ileana L. Piña, Tariq Ahmad, Eric Leifer, Lawton Cooper, Patrice Desvigne‐Nickens, Mona Fiuzat, Kirkwood Adams, Justin Ezekowitz, David J. Whellan, James L. Januzzi, Christopher M. O’Connor, G. Michael Felker   +14 more
doaj   +1 more source

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources

Serum NT-ProBNP potential marker of cirrhotic cardiomyopathy

Folia Medica, 2022
Introduction: Based on many previous studies, liver cirrhosis is traditionally associated with cardiac dysfunction. The main clinical features of cirrhotic cardiomyopathy include attenuated systolic contractility in response to physiologic or pharmacologic strain, diastolic dysfunction, electrical conductance abnormalities, and chronotropic ...
Maya Risteska, Ludmila Vladimirova-Kitova, Vladimir Andonov   +2 more
openaire   +3 more sources

Prognosis and NT-proBNP in heart failure patients with preserved versus reduced ejection fraction

Heart, 2019
Background We assessed the prognostic significance of absolute and percentage change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in patients hospitalised for acute decompensated heart failure with preservedejection fraction (HFpEF ...
K. Salah, S. Stienen, Y. Pinto, L. Eurlings, M. Metra, A. Bayés‐Genís, V. Verdiani, J. Tijssen, W. Kok   +8 more
semanticscholar   +1 more source