Results 31 to 40 of about 437,978 (246)
The need for greater opioid pharmacovigilance in COPD
International Journal of COPD, 2017 Nicholas T Vozoris1–3 1Division of Respirology, Department of Medicine, St Michael’s Hospital, Toronto, ON, Canada; 2Keenan Research Centre in the Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada; 3Department
Vozoris NT
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Engaging Remote Aboriginal Communities in COVID-19 Public Health Messaging via Crowdsourcing
Frontiers in Public Health, 2022 Health comunication is a critical component of pandemic mitigation, but mainstream prevention messaging often lacks social, cultural and linguistic relevance to vulnerable populations.
Miriam Glennie +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Toward wafer-scale diamond nano- and quantum technologies
APL Materials, 2019 We investigate native nitrogen vacancy (NV) and silicon vacancy (SiV) color centers in a commercially available, heteroepitaxial, wafer-sized, mm thick, single-crystal diamond.
Richard Nelz +10 more
doaj +1 more source
Respiratory Medicine Case Reports, 2019 Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse ...
Madeleine Haygarth +5 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Preserving Privacy in the Face of Clients with Different Data Needs Using the NGLMS
International Journal of Population Data Science, 2017 Objectives SA NT DataLink’s Next Generation Linkage Management System (NGLMS) provides a novel approach to handling privileged or sensitive data for certain projects without having to replicate or duplicate databases and work to protect privacy.
Chris Radbone, James Farrow
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Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Clinical utility of guanfacine extended release in the treatment of ADHD in children and adolescents
Patient Preference and Adherence, 2015 Nicholas T Bello Department of Animal Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA Abstract: Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric illness in children and adolescents.
Bello NT
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