Results 31 to 40 of about 454,601 (198)

From additivity to mirativity: The Cantonese sentence final particle tim1

Glossa, 2018
This paper studies the Cantonese sentence final particle tim1 and more generally the semantics of additive particles. The range of meanings conveyed by tim1 appears quite broad, covering both scalar and non-scalar additive readings as well as mirative ...
Daniel Tsz-Hin Lee, Grégoire Winterstein, Regine Lai, Zoe Pei-Sui Luk   +3 more
doaj   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Toward wafer-scale diamond nano- and quantum technologies

APL Materials, 2019
We investigate native nitrogen vacancy (NV) and silicon vacancy (SiV) color centers in a commercially available, heteroepitaxial, wafer-sized, mm thick, single-crystal diamond.
Richard Nelz, Johannes Görlitz, Dennis Herrmann, Abdallah Slablab, Michel Challier, Mariusz Radtke, Martin Fischer, Stefan Gsell, Matthias Schreck, Christoph Becher, Elke Neu   +10 more
doaj   +1 more source

Bilateral diffuse pulmonary infiltrates secondary to malignant peritoneal mesothelioma – A rare clinical presentation

Respiratory Medicine Case Reports, 2019
Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse ...
Madeleine Haygarth, Kyi Kyi Zaw, Victoria Yachmenikova, Adrian M.J. Pokorny, Kin Keung Kwong, Subash S. Heraganahally   +5 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Clinical utility of guanfacine extended release in the treatment of ADHD in children and adolescents

Patient Preference and Adherence, 2015
Nicholas T Bello Department of Animal Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA Abstract: Attention deficit hyperactivity disorder (ADHD) is the most common psychiatric illness in children and adolescents.
Bello NT
doaj  

Weaving care praxis to mediate glitches in Indigenous digital land management in northern Australia

Digital Geography and Society
Digital technologies increasingly entangle with everyday Indigenous land management practices, from place-based biocultural monitoring to political decision-making. As Indigenous knowledge and governance practice intersect with big data and technological
Jennifer Mairi Macdonald, Cathy J. Robinson, Danilo Urzedo, Cara Penton, Recain Nabarlambarl, Lorina Maralngurra, Suzanna Nabulwad, Amanda Lilleyman, Sylvia Maroney, Gloria Roberts, Anthea Lawrence, Lydia Lawrence, Lewellyn Moulin, Bernadette Calma, Bessie Coleman   +14 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Preserving Privacy in the Face of Clients with Different Data Needs Using the NGLMS

International Journal of Population Data Science, 2017
Objectives SA NT DataLink’s Next Generation Linkage Management System (NGLMS) provides a novel approach to handling privileged or sensitive data for certain projects without having to replicate or duplicate databases and work to protect privacy.
Chris Radbone, James Farrow
doaj   +1 more source