Results 111 to 120 of about 333,753 (297)

Analysis of CF···FC interactions on cyclohexane and naphthalene frameworks [PDF]

, 2014
The authors thank EaStCHEM, the Royal Society (for a Wolfson Merit Award for D.O’H.) and CNPq and FAPESP are also gratefully acknowledged for the studentships (to R.A.C.
Rodrigo A. Cormanich (1751113), Cormanich, Rodrigo A., Rittner, Roberto, Roberto Rittner (364724), O'Hagan, David, Michael Bühl (1317231), David O’Hagan (1313640), Buehl, Michael   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A complementary study of perovskites : combining diffraction, solid-state NMR and first principles DFT calculations [PDF]

, 2011
Perovskites, ABX₃, and their associated solid-solutions are a particularly important and attractive area of research within materials chemistry. Owing to their structural and compositional flexibility and potential physical properties they are one of the
Johnston, Karen Elizabeth
core   +1 more source

Investigation into the radioactivity of various natural and anthropogenic radionuclides in marine sediments from the Sudanese coastline of the Red Sea

Scientific Reports
A total of sixty surface sediment samples were systematically obtained from ten distinct locations along the Sudanese coastline of the Red Sea during the summer season (June 2016) and the winter season (February 2017), subsequently analyzed using high ...
Elshafeea Abowslama, Mohamed Eltayeb, Khalid Elmamoun Ibrahim, Tarig Elshaarani, Mossap Babikir, Ekrami Osman, Gosai Abdelgader, Nuha Tarig, Nasreen Hassan, Mashaer Khalied, Fatima Elbasheer, Mohammed AbdulRahman, Alfatih Osman   +12 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Arctic Ozone Hole and Enhanced Mid‐Latitude Ozone Losses Due To Heterogeneous Halogen Chemistry Following a Regional Nuclear Conflict

Earth's Future
In a global‐scale nuclear war, massive explosions, intense heat, and radioactive fallout would cause extensive harm to humanity and ecosystems. Further, previous studies of even regional‐scale nuclear conflicts show that the smoke from large‐scale fires ...
Simchan Yook, Susan Solomon, Charles G. Bardeen, Kane Stone   +3 more
doaj   +1 more source

Chemistry of nuclear particle production in 32 A MeV 136,124Xe+124,112Sn reactions and nuclear symmetry energy*

EPJ Web of Conferences, 2012
Nuclear particle production from peripheral to central events is presented. N/Z gradient between projectile and target is studied using the fact that two reactions have the same projectile+target N/Z and so the same neutron to proton ratio for the ...
Kabtoul M., Bougault R., Colonna M., Galichet E.   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Nuclear Chemistry: An Introduction [PDF]

, 2003
This lesson is an introduction to nuclear chemistry. It reviews alpha, beta and gamma decay reactions, the concept of half-life, and nuclear fission and fusion.
Carpi, Anthony, Anthony Carpi
core