Results 121 to 130 of about 3,958,335 (294)
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
, 2010 This 2010 edition of Nuclear Energy Data , the OECD Nuclear Energy Agency's annual compilation of official statistics and country reports on nuclear energy, provides key information on plans for new nuclear plant construction, nuclear fuel cycle ...
Agency, Nuclear Energy
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Developing a survey instrument to evaluate tertiary chemistry students' attitudes and learning experiences [PDF]
, 2001 New Zealand tertiary institutions, like others worldwide, have experienced a decline in science and chemistry enrolments in recent times as students seek other career paths that they perceive to be more lucrative.
Dalgety, Jacinta +3 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Graduate Study in Chemistry, The University of Texas at Austin, circa 1977
, 1977 Table of Contents: Foreword (p. 3) -- The University (p. 4) -- The Austin Community (p. 6) -- Texas and Central Texas (p. 10) -- The Chemistry Department (p. 14) -- Research Specializations (p. 20-81) -- Analytical Chemistry (p.
Chemistry Department
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Lapatinib-Based Radioagents for Application in Nuclear Medicine
Applied SciencesLapatinib is an approved therapeutic agent for the treatment of HER2-positive breast cancer. It has a high affinity for the non-receptor cytoplasmic tyrosine kinases of the EGFR and HER2 receptors. It is a type II inhibitor, with Kiapp values of 3 nM and
Przemysław Koźmiński, Ewa Gniazdowska
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Department of Chemistry Newsletter (Spring 1981, No. 4)
, 1981 The newsletter of the Department of Chemistry, published once or twice a year, highlights people, events, and facilities. Content includes brief articles on new faculty hires, faculty and staff retirements, obituaries, major facilities and equipment ...
Department of Chemistry
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