Results 131 to 140 of about 3,224,901 (376)
Nuclear particle production from peripheral to central events is presented. N/Z gradient between projectile and target is studied using the fact that two reactions have the same projectile+target N/Z and so the same neutron to proton ratio for the ...
Kabtoul M. +3 more
doaj +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Two new group separation schemes, based on ion exchange chromatography, for the selective and quantitative isolation of rare earth elements (REE) from accompanying elements, were devised.
Dybczyński Rajmund S. +6 more
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Bohr: Physique atomique et connaissance humaine/Becker: Theorie der Elektrizität Bd. I/Schaefer und Päsler: Einführung in die Theoret. Physik Bd. I/MacDonald: Thermoelectricity: An Introduction to the Principles/Brillouin: Science and Information Theory/Bradley: Shock Waves in Chemistry and Physics/Pirani und Yarwood: Principles of Vacuum Engineering/Chase: Nuclear Pulse Spectrometry [PDF]
Klaus Pöschl +7 more
openalex +1 more source
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
From 1993 to 2013, tacrine was an approved drug for Alzheimer’s disease. Due to its strong inhibitory properties towards cholinesterase, tacrine causes an increase in the level of the neurotransmitter acetylcholine in the cholinergic system of the ...
Przemysław Koźmiński, Ewa Gniazdowska
doaj +1 more source
Recent Advances in Nuclear Forensic Chemistry.
Mark D. Straub +3 more
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Lapatinib-Based Radioagents for Application in Nuclear Medicine
Lapatinib is an approved therapeutic agent for the treatment of HER2-positive breast cancer. It has a high affinity for the non-receptor cytoplasmic tyrosine kinases of the EGFR and HER2 receptors. It is a type II inhibitor, with Kiapp values of 3 nM and
Przemysław Koźmiński, Ewa Gniazdowska
doaj +1 more source

